Ninetails (Okami)

Ninetails ( Or Demon Lord Nintails, Lord of Ryoshima Cost, as he calls himself) is the main villain of the 2nd act of Okami.

Before Amaterasu and Issun made it to Ryoshima Coast, he murdered the priestess, Rao in cold blood, and took her form. Using that form, he tricked the two heroes into going to the sunken ship to obtain the Fox Rods, a tool that could turn the tide of the war, but they weren't there, so he left them for dead when the Water Dragon attacked.

The Fox Rods were actually located inside the Water Dragon, and Amaterasu handed them over to him. After that, Amaterasu and Issun were shown what happened to the real Rao, they made their way to Queen Himiko's palace, where he had murdered the queen, so that his stronghold, Oni Island, could not be found. Still disguised as Rao, his tricks stopped working, and he fought Amaterasu in Rao's form and lost. Later, on the top of Oni Island, he fought Ammy again, this time using his own brush powers, but after losing his tails, he was revealed to be a scrawny, one-eyed fox, and was quickly dispatched. Later on, he is fought again on the Ark of Yamato.