User blog comment:DragonDude83/PE Proposal: Mysterio (Spider-Man: Shattered Dimensions)/@comment-39032584-20190515190450

Woah... while the whole concept of destroying the world, universe, or in this case, the multiverse, has been done many, many times by now (for instance, the last villain I proposed had a variation of the same main goal), I certainly wouldn't have expected that from Mysterio, and I imagine that still stands out as very heinous in pretty much any Spider-Man video game. Therefore, I'm voting yes for now.

P.S. According to something I just read, he also apparently went on a destructive rampage of sorts when he collected one of the tablet fragments, so that only increases my conviction that he does enough to qualify.