Drej Queen Susquehana

""The human threat ends now.""

- - The Drej Queen while speaking in her native Drej language.

The Drej Queen is the main antagonist of "Titan A.E." and she is the leader of an energy-based alien race called the Drej. Unlike her drone followers, only she has eyes.

Her intentions are to extinguish the human race from the universe. She talks, but doesn't speak English, but a strange alien language (with her dialogue being completed with English subtitles) which is problably the native dialect of her people.

In the end, along with her followers, she is destroyed by the Cale using the project Titan.

Although a female, she is voiced by Christopher Scarabosio.