Orochi (Okami)

Yamato no Orochi (often just called Orochi') is an eight headed dragon who is the main antagonist for the first half of Okami. It's main head is the fire head, which speaks for all the other heads, with the most clueless being the lightning head, which is in the opposite position of the fire head.

100 years in the past
A century before the beginning of the game, Wakka and the Celestials fled there tribe on the Moon to the Celestial Plane, where the gods lived, in the Ark of Yamato. However, Orochi and a hoard of demons ambushed them. At the same time, Yami and other evil creatures that were hiding inside the ark starting massacring the Celestials. Only Wakka managed to escape by crashing the Ark of Yamato on Earth, but then Orochi, Yami, the demons and all other forms of evil spread around the Earth.

Orochi took refuge in the Moon Cave and started forcing the residents of Kamiki Village to sacrifice young women to him as food or else he would destroy there village. After many sacrifices, Amaterasu, the reincarnation of the sun god Shiranui from a century later appeared in Kamiki and was mistaken for Shiranui. After Nami was marked for sacrifice, Amaterasu dressed the great warrior, Nagi, as Nami and took him to Orochi's lair, in which Amaterasu and Orochi began a long battle. Nagi (AFTER taking off the woman's clothing) then attacked finished off Orochi with help from Amaterasu.