Nefasturris

Nefasturris (lit. "Tower of Sin" in Latin), also callled the "Tower of Misery" is a giant skyscraper-possessing demon monster and a minor villain from Devil May Cry 2.

Devil May Cry 2
This mutant monstrousity that appears as a giant undead humanoid with half its body covered with black-reddish oozing color and spikes on its back, is made up of thousands of bat-like demons, which also serve as energy conduits between the giant and the Demon World. Those creatures, when combine within a skyscraper, creates the form of a giant humanoid that emerges from the building.

After its first form is defeated and destroyed, its decapitated head comes to life and continues to fight on as Nefascapitas (lit. "Head of Sin" in Latin), the "Head of Disaster".

Nefasturris is the boss for Mission 6 of Dante's scenario in Devil May Cry 2. It emerges from a skyscraper within the streets of Uroboros City, but Dante beats it down, eventually slaying the Nefascapitas, and continues on to stop Arius.

Nefasturris later reappears as a component of Argosax the Chaos.

Trivia

 * Nefasturris is one of the largest demons in the Devil May Cry series.
 * The "Nefas-" in the names of its forms was mistranslated as "disaster" in the enemy files and "misery" in the Guidepost of Devil May Cry 2.
 * Nefasturris is considered one of the most disturbing demons in the game, the other being Nightmare and Argosax.
 * Nefasturris bears some similarity to the demons featured in DmC as both are shown to have porcelain bodies that break away, revealing black, ink like matter.