Saint of Killers

"He's a beast straight out of Hell. But he doesn't want Genesis for himself, he wants to kill it, and you. And there's nothing you can do to stop him."

- Fiore describing to Jesse about Saint of Killer

The Saint of Killers (aka William) is the central antagonist of the Preacher comic book series and AMC's television series.

During 1800s, he earned the nickname, the Butcher of Gettysburg. After he died, he was sent to Hell. There, he was forced to relive his family's death over and over. Each time, he slaughtered everyone in Ratwater as vengeance for all eternity. The man eventually had a visit from DeBlanc and Fiore, where they offered to release him from Hell if he killed Jesse Custer.

After being released from Hell, the Saint is hellbent on killing Jesse. Eventually, the Saint of Killers was given an extract of Jesse's soul, making him vulnerable to Genesis. He was then locked up in a truck beneath the Angelville swamps. He was later used by the Grail, only to be turned over to Superintendent Mannering.

Personality
The Saint has a very vengeful man. Though despite his fearsome reputation, the Saint was a loving husband and father, attempting to live a normal life and doing everything in his power to protect his family. However, when they died, the last piece of good in him died as well, with his soul literally shattering into peaces and scattering across the world. In his fury, he slaughtered the entire town of Ratwater, including the children as an act of vengeance. Upon his resurrection, he is shown to be a very remorseless killer, as he ruthlessly slaughters anyone who gets in his way. After Jesse tricks and traps him, he becomes fixated on exacting revenge on the preacher. Despite lacking a soul, he still deeply cares for his family, as talking about them is a certain way to expose his wrath. The Saint went as far as to rip out Sidney's eyes for making fun of their deaths and kill Satan for his involvement in their deaths and for torturing him. He also seems to have developed somewhat of a compassion for Eugene, sticking up for him whenever Satan struck him.