Dr. Pickman

Dr. Pickman is a main antagonist of 2007 survival horror game, Manhunt 2. He is the one responsible for what happend to Daniel Lamb, also being the head researcher of the Pickman Project Facility, specializing in brainwashing and drugs manufacturing for military purposes.

Biography
Dr. Pickman is a genius scientist who created the Pickman Project Facility. After his cruel methods of experimentation were exposed by the government, they stopped funding his experiments, so he resorts to underground researches. After creating his greatest invention Pickman's bridge - device which  allows two personalities to co-exist, while they are not aware of each other - Pickman requires a human test subject. Daniel Lamb, his co-scientist, voluntarily becomes a test subject. Pickman's bridge mulfunctions, resulting in Daniel Lamb being able to communicate with his second personality Leo Kasper, which leads to Daniel murdering his wife with a kitchen knife while being posessed by Leo's murderous personality. Pickman hypnotiezed Daniel in order to induce total memory loss and placed him in a Dixmore mental institution for 6 years. Meanwhile, he continued his experiments. After escaping and finding out Pickman's whereabouts, Daniel infiltrates into the research facility, pursues Pickman, renders him unconcsious with a tranquilizer gun and ties to a chair. Daniel, posessed by Leo again, tries to force Pickman to remove the Bridge from Daniel's head, while Pickman calmly explains to Leo that with removal of the device, his personality will disappear from Daniel's head. He then tries to convince Leo to untie him and even goes so far as using the code phrase meant to erase all Daniel's memories, but before passing out, Leo grabs a scalpel from nearby table and stabs Pickman three times in the heart, ending his life.

Pickman makes his last appearance as a thought-form hunter inside Daniel's mind, who claims that he didn't deserve to die and his experiments are not over and chases Daniel around with a tranquilizer gun.

Personality
Pickman is a cruel, emotionless and calculative person, who will go to any lengths to achieve his goals. He is always calm and collected, even when he appears in person in Dixmore asylum while patients and personnel are fighting around him and when he is tied to a chair and interrogated by Leo, ordering and threatening him in a relaxed manner.

He seems to be involved enough to roam the territory of the researching facility on his own, seeking intruders and ordering his henchmen, but retreats deeper into the building after realising that such dangerous individual as Daniel Lamb is inside the facility. Pickman shows some degree of marksmanship proficiency while trying to defend himself from Daniel with a tranquilizer gun.