Madame Margaret

Madam Margaret, also known as Madam Margie, is the evil leader/principal of St. Rita's Prepartory School. She has a profound hatred for boys, due to how she was teased by her brothers. Her goal and desire was to make a utopia of all girls and no boys. Apparently, she has the ability to communicate with her younger self and vice versa through time.

In Operation: F.U.T.U.R.E.  Numbuh 4 was sent to Madam Margaret's boarding school, unaware of her evil intentions, and almost got turned into a girl. Luckily, he escaped but had to hide and try to be safe. So as a result, in the future, because he lost that battle, girls ruled the world and harrassed all the boys they could find. Luckily, Numbuh 4 had his own group of heroes known as the Boys Nest Door, who saved boys from the girls. Eventually, they had one final war with the girls, along with a rebellion of the Girl Squad, known as Sally Sanban, and almost were defeated. But Numbuh 4 confronted Madam Margaret again and went back in time to warn the KND about Madam Margaret. Madam Margaret had tried to follow Numbuh 4 into the time he had just traveled to, but Sally Sanban crushed the time machine so Madam Margaret couldn't follow him there. Once he got there, he warned the KND of Numbuh 4, his present self, being chased by the girl squad. Future Numbuh 4 had then led the Kids Next Door to the battlefield and rescued Numbuh 4. Once Numbuh 4 had been rescued from Margaret and her Girl Squad, Numbuh 3 was sent in with H.I.P.P.I.E. H.O.P. to take them down. The Girl Squad attempted to destroy H.I.P.P.I.E.-H.O.P. with the Girlifying Rifles, but much to Margaret's dismay, the robot was too girly for them to destroy. Numbuh 3 then crushed her time machine and stopped her from contacting her future self, making the Girl Squad forever non-existant. Margie was sent to the Kids Next Door Artic Prison and the school had then crashed down and 75 years later, on those same grounds, was a playground built for boys and girls.