User blog:Loolveus/Diagonsing disorders in certain villains

DISCLAIMER: I am not a doctor most of what my assumptions will be are purely from my own research and guesses.

This idea came about after I saw Pokemon: Detective Pikachu which features a wheelchair-bound main antagonist who suffers from a disorder that caused him to lose the use of his legs and become much weaker. I only have two of these characters btw so this may be a waste of time but ah well.

Howard Clifford
Really nothing is known about his disease other than caused him to lose the use of his legs and made him significantly weaker which prompted him to want the body of Mewtwo which would make him stronger and grant him leg mobility again.

My guess is he has Becker's muscular dystrophy as one photo in the movie suggests he lost the use of his legs when he was already an older guy and when people who suffer from this particular version of MD get to their 50s to 60s that's when they tend to lose the use of their legs and symptoms are usually less severe which can evident from Howard since he seems to have no problem with other areas of his body than probably just his limbs. Again this is me just guessing and I'm probably wrong.

Doctor Octopus (Marvel's Spider-Man)
Now usually when you hear of a disorder that doesn't affect your brain but causes a loss of the ability to use your muscles use you'd usually think of ALS/Motor Neuron Disease and while I thought this wasn't the case with Doc Ock at first apparently there are environmental factors that fit into Otto's description since he said his doctor's told him it could have related to toxic exposure in his youth. According to the ALS Association things such as metals, solvents, radiation and electromagnetic fields can all contribute to ALS, which is supported by Doc Ock'scientific background.