Spider Queen (Okami)

Spider Queen is a villain from the video-game Okami and is a powerful but ultimately malevolent spirit that takes the form of a grotesque featureless female face with the torso of a spider, gnarled humanlike hands on the end of her legs and a strange growth on her back resembling a nightmarish "flower" made out of human eyes.

Spider Queen is also known in Japan as the "prostitute spider" - suggesting that despite her horrific form she is quite a perverse and/or carnal creature: even in death Spider Queen returns as a ghost to torment Okami later in the game.