User blog comment:Alwaysmore2hear/Nominate Your Essential Villains for the 2018 FANDOM 100/@comment-32898255-20180911181948

I think Erik Killmonger or Thanos would be the best choices, as they impacted not only the MCU, but their world with Wakanda revealing itself to the world as Thanos literally wiped out half of the universe (and he lived up to the hype he was given since the post-credits scene of The Avengers.