George, Ralph and Lizzie

George, Ralph, and Lizzie are the secondary antagonists of the 2018 monster action film Rampage based on the classic arcade game of 1986 of the same name.

History
Primatologist Davis Okoye has been caring all his life for George, a silver-back albino gorilla, that he saved when it was a year old, at the San Diego Wildlife Sanctuary.

However, a strange genetic experiment left by the scientist Claire Wyden accidentally falls into the habitat of George, infecting him. With the passing of the days, the gorilla begins to grow hugely and adopt aggressive and savage behavior.

Okoye assumes that the experiment had something to do with George's problem, so along with Dr. Kate Caldwell is taken to an agency led by agent Harvey Russell who tells him about the "Rampage Project".

Russell explains that two other animals have also been infected: a gray wolf named Ralph and an American crocodile named Lizzie. After escaping from the sanctuary, George begins to cause panic in the city but is quickly incapacitated and taken in a helicopter to the facilities of the agency.

George, having adopted a huge force, is freed from his imprisonment and knocks down the helicopter causing it to crash in the middle of the city. To make matters worse, Ralph flees his captivity in the direction of San Diego while Lizzie managed to enter the river, making his way to the same area as George and Ralph.

The three animals begin to cause panic, death and destruction around North America, destroying everything in their path while fighting for supremacy.

Meanwhile, Okoye is forced, along with Caldwell, to find an antidote before George, Ralph and Lizzie cause a worldwide catastrophe.

Powers and Abilities
After being infected, George, Ralph and Lizzie have grown enormously. All three have developed great intelligence, strength and superhuman speed, being difficult to tame.

The most remarkable thing about Ralph is the ability to unfold wings with which he can fly, while Lizzie has a skin collar that opens when she feels threatened.

Personality
Little is known about the origins of Ralph and Lizzie, however George always showed a gentle and charismatic behavior in front of everyone in the sanctuary. After being infected, all three have shown fierce and aggressive behavior.

Trivia

 * In the original game, George, Ralph and Lizzie are humans who mutated into animals. However, in the film they are animals mutated to gigantic proportions.
 * George, Ralph and Lizzie are portrayed as protagonist villains in the video game; in the film it is the first time that their roles are inverted to make two of them (Ralph and Lizzie) the secondary antagonists.