Yzma from The Emperor’s New Groove
The Grand High Witch from The Witches
Barty Crouch Jr. turned Draco Malfoy into a ferret.
The Joker from the Nolanverse
Dr. Hibbert from Treehouse of Horror XIII
Does Nina's dad from FMA count? Or is it different?
Amazing Spider-Man's Curt Connors tried to turn the New Yorkers into mutant lizards
Yzma forced Kuzco into a llama and Dr. Facilier turned Naveen and Tiana into frogs
The Coachman from Pinocchio turned young boys into donkeys.
What do you think?