Well, all of them, they're all pricks.
As for who's the biggest one...I'd say Crimson. The others at least don't want their children to die from what I read. Crimson abused Moxxie for years, made him see that he killed his mother, molded him into a hitman (if a moral one), never bailed him out of jail, forcefully married him off to his creepy ex, threatened to kill him, and now seems to be ready to fulfill that threat.