Achira is the main antagonist of the Extreme Ghostbusters episodes Darkness at Noon Part 1 & 2. She is the demon spawn of Duaka. Her name is derived from the Mesopotamian word Achiratima, roughly translated to "Destroyer of Civilizations."
She was voiced by Susan Tyrell.
Achira's function is to spread her disease and decay on cities in order to fulfill the eleventh prophecy. Her repeated method of destruction involves taking on a willing host and releasing a plague, which causes victims to grow disgusting blotches on their faces, some form of cross-dimensional dermo-transmogrification (informally referred to by Garrett Miller as "ghost zits"). The zits on the peoples faces are her offspring that need a host to grow.
Thousands of years ago, Achira was imprisoned within an underground structure in conjunction with using incantations and talisman objects. However, she was released a group of subway workers in present-day New York City. Ghostbuster veteran Egon Spengler attempts to round up new members of his team, but unfortunately one of them named Kylie Griffin stole a Ghost Beacon to summon the spirit of her dead grandmother Rose. Taking the opportunity, Achira poses herself as Rose to possess Kylie for spread a new epidemic.
However, the other teams of the new team arrive to the rescue to free Kylie from Achira's control, and Kylie teams up with the Ghostbusters to defeat Achira as she summoned up her offspring to attack the world. Having updated their equipment, the new Ghostbusters manage to defeat and capture Achira, and she was placed into the Containment Unit for the rest of the life, much to her anger.