How would you like your tombstone to read, Spider-Man... or Peter Parker?
~ Alistair to Spider-Man.

Dr. Alistair Smythe was the creator of the S-Bots, also known as the "Spider-Slayers". He appears in the video game, The Amazing Spider-Man as the main antagonist. He was the creator of cutting-edge robotics. His genius was as massive as his ego.

He was voiced by Nolan North, who also voiced Dr. Edward Richtofen, Martin Walker, David, and Magni.

History

Alistair Smythe grew up as an only child in Brooklyn, New York. The son of Spencer Smythe, a single father whose work always took precedence over family, young Alistair grew up with no motherly influence as he adapted to a childhood of neglect. During his high school years, Alistair was surprised to find his father make a concerted effort to atone for his faults as a parent. Only months before dying of radiation poisoning (itself a lab accident gone awry), Spencer passed along all of his knowledge of robotics and technology to Alistair – years of research that Alistaire absorbed with full comprehension in mere weeks.

At Empire State University, Smythe was roommates and close friends with a young Curt Connors. The two geniuses shared a playful rivalry, frequently arguing over the merits of technology versus biology. But Smythe's beliefs were not as popular, and he lost several prominent grants to Connors. Their steadfast friendship started to show cracks...

As he struggled to gain funding for his work in robotics and nanotechnology, Smythe watched Connors join the prestigious OsCorp Industries, and rapidly rise through its ranks. Jealousy began to fester in his heart...

Smythe was devastated by the accident that turned Connors into the Lizard, but as fate would have it, it was also his greatest boon. After Connors’ inglorious dismissal from the company, OsCorp hired Smythe and funneled all of Connors’ resources to its new robotics division. Smythe became “the new face of OsCorp,” determined to change the world, and erase the stain of Connors’ biological freak show. But Connors' legacy would not be that easy to destroy. During the removal of the cross-species specimens, Smythe and his scientists were infected by their virus. The control of Smythe prided himself on began to slip away; his vengeance led him to program robots to destroy cross-species who escaped the OsCorp quarantine. His greed led him to inject himself with an untested cure, a mistake that took the use of his legs.

The order Smythe built around himself collapsed into chaos. Instead of wasting time to develop a cure, he was more determined than ever to eliminate the infected, including Spider-Man. Smythe's robots caused more harm than good, and put many innocent lives at risk. He was ultimately dismissed from OsCorp and forced to take sole blame for the outbreak. This fueled Smythe's rage more, as he released his most deadly wave of robots on the city. It was an all out extermination.

Spider-Man and the Lizard formed an uneasy alliance to stop Smythe, and manufactured a successful cure capable of saving the city. At this point, all threats were ceased and the city was saved. Smythe was back inside one of his robot labs in OsCorp Tower and was almost completely infected from the virus, as he wasn't able to get the cure. It was too late, however, and so the regretful Doctor Alistaire Smythe committed suicide by way of programming one of his own hunter bots to shoot him.

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          508759 thumb.png Villains

Comics
Abomination | Absorbing Man | Agony | A.I.M. | Alistair Smythe | Annihilus | Answer | Arcade | Arnim Zola | Awesome Android | Baron Zemo II | Basilisk | Beetle | Beyonder | Black Cat | Blackie Drago | Blastaar | Blizzard | Blob | Bombshell | Boomerang | Brothers Grimm | Burglar | Bullseye | Bushwacker | Cadaverous | Calypso | Carlton Drake | Carnage | Carrion | Chameleon | Chance | Constrictor | Crime Master | Crossbones | Daemos | Dark Avengers | Deadpool | Demogoblin | Diablo | Doctor Doom | Doctor Faustus | Doctor Octopus | Doppelganger | Dormammu | Electro | Enforcers | Equinox | Fancy Dan | Firelord | Freak | Frightful Four | Ghost | Gog | Goliath | Grant Ward | Graviton | Green Goblin (Norman Osborn, Harry Osborn and Bart Hamilton) | Grey Goblin | Grizzly | Hammerhead | Hand | Hazmat | High Evolutionary | Hitman | Hobgoblin | Hood | Human Fly | Hybrid | HYDRA | Hydro-Man | Inheritors | Iguana | Jackal | Jack O' Lantern | Jigsaw | J. Jonah Jameson | Johnny Ohm | Jonas Harrow | Juggernaut | Justin Hammer | Kaine | Karn | Killer Shrike | King Cobra | Kingpin | Knull | Kraven the Hunter | Lasher | Lady Deathstrike | The Leader | Lightmaster | Living Brain | Living Laser | Lizard | Loki Laufeyson | Madame Masque | Madame Viper | Maestro | Magneto | Mandarin | Man-Spider | Man-Wolf | Mania | Masters of Evil | Menace | Mephisto | Mesmero | Mister Brownstone | Mister Fear | Mister Hyde | Mister Negative | Mojo | Molten Man | Montana | Morbius | Morlun | Moses Magnum | Mysterio | (Quentin Beck, Daniel Berkhart and Francis Klum) | Nekra | Nightmare | Niles Van Roekel | Nitro | Onslaught | Overdrive | Owl | Ox | Phil Urich | The Prowler | Psycho-Man | Puma | Punisher | Punisher (Earth-95126) | Ramrod | Raze | Red Ghost | Red Skull | Rhino | Rhino II | Richard Fisk | Ringer | Riot | The Rose | Roxxon Energy Corporation | Sabretooth | Sandman | Sauron | Scarecrow | Scorcher | Scorpion | Scorn | Scream | Sebastian Shaw | Secret Empire | Sentinels | Seth Youngblood | Shocker | Shriek | Silver Sable | Sinister Six | Skip | Skrulls | Solus | Patton Parnel | Spider-Man Revenge Squad | Spider-Slayers | Spot | Street | Super-Apes | Supercharger | Swarm | Symbiotes | Tarantula | Taskmaster | Terminus | Thunderball | Thunderbolts | Tinkerer | Titania | Titanium Man | Tombstone | Trapster | Tyrannus | Ultimatum | Ultron | Venom (Eddie Brock) | Vermin | Vulture | Walrus | Whiplash | White Rabbit | Whirlwind | Will-O'-The-Wisp | Wizard | Worthy | Wrecker | Zodiac | Zombie Spider-Man | Zombie Giant-Man

Movies
Spider-Man: Green Goblin | Dennis Carradine | Bank Robbers | Harry Osborn | J. Jonah Jameson
Spider-Man 2: Doctor Octopus | Harry Osborn | J. Jonah Jameson | Green Goblin
Spider-Man 3: Venom | Sandman | New Goblin | J. Jonah Jameson | Green Goblin | Dennis Carradine
The Amazing Spider-Man: Lizard | Gustav Fiers | Cash Register Thief | Norman Osborn
The Amazing Spider-Man 2: Electro | Green Goblin | Donald Menken | Rhino | Alistair Smythe | Ashley Kafka | Felicia Hardy | Gustav Fiers | Norman Osborn
Spider-Man: Homecoming: Bestman Salvage (Vulture, Tinkerer, Shocker #1, Shocker #2 & Randy Vale) | Mac Gargan | Aaron Davis
Spider-Man: Into the Spider-Verse: Kingpin | Doctor Octopus | Prowler | Tombstone | Scorpion | Green Goblin | Vanessa Fisk | Richard Fisk
Spider-Man: Far From Home: Mysterio's Crew (Mysterio, William Ginter Riva, Victoria Snow, Gutes Guterman, Janice Lincoln, & Doug) | Elementals (Molten Man, Hydro-Man, Sandman, Cyclone and Elemental Fusion) | Skrulls (Talos) | Obadiah Stane | J. Jonah Jameson

Television
Spider-Man (1967)
Vulture | Green Goblin | Electro | Rhino | Mysterio | Doctor Octopus | Scorpion | Human Fly | Kingpin | Lizard | Spider-Slayer | Sandman | Dr. Matto Magneto | Enforcers (Cowboy and Ox) | Frederick Foswell | J. Jonah Jameson

Spider-Man (1981)
Doctor Doom | Kingpin | Doctor Octopus | Lizard | Black Cat | Sandman | Magneto | Mysterio | Ringmaster | Green Goblin | Sidewinder | Kraven the Hunter | Red Skull | Chameleon | Vulture | Hammerhead | Wizard

Spider-Man and His Amazing Friends
Green Goblin | Kraven the Hunter | Doctor Doom | Swarm | Chameleon | Electro | Brotherhood of Mutants (Magneto, Blob, Toad and Mastermind) | Mysterio | Loki Laufeyson | Ymir | Mordred | Kingpin | Doctor Faustus | Red Skull | Juggernaut | Shocker | Sandman | Dracula | Scorpion | Beetle | Doctor Octopus | A.I.M.

Spider-Man: The Animated Series
Kingpin | Green Goblin (Norman Osborn and Harry Osborn) | Doctor Octopus | Hobgoblin | Venom | Vanessa Fisk | Richard Fisk | Insidious Six (Scorpion, Rhino, Mysterio, Chameleon, Shocker and Vulture) | Black Cat | Lizard | Morbius | Spider-Carnage | Spider-Slayers (Alistair Smythe) | Carnage | Baron Mordo | Dormammu | Silver Sable | Hydro-Man | Prowler | Doctor Doom | Red Skull | Electro | Hammerhead | Tombstone | Kraven the Hunter | Calypso | Herbert Landon | Jackal | Spot | J. Jonah Jameson

Spider-Man: The New Animated Series
Harry Osborn | Electro | Kraven the Hunter | Turbo Jet | Kingpin | Lizard | Shikata | Silver Sable

The Spectacular Spider-Man
Green Goblin | Tombstone | Doctor Octopus | Hammerhead | Venom | Sinister Six (Rhino, Vulture, Electro, Sandman, Mysterio and Kraven the Hunter) | Chameleon | Tinkerer | Enforcers (Shocker, Ricochet and Ox) | Molten Man | Silver Sable | Harry Osborn | Lizard | J. Jonah Jameson | Black Cat | Miles Warren | Frederick Foswell | Calypso | Roderick Kingsley | Morris Bench | Cletus Kasady

Ultimate Spider-Man
Doctor Octopus | Green Goblin | Harry Osborn | Taskmaster | HYDRA (Arnim Zola, Crossbones, Morbius and Baron Mordo) | Sinister Six (Kraven the Hunter, Rhino, Electro, Scorpion, Vulture & Hydro-Man) | Batroc the Leaper | Beetle | Lizard | Frightful Four (Wizard, Trapster & Klaw) | Juggernaut | Sandman | Venom | Loki Laufeyson | The Collector | Grandmaster | Carnage | Wolf Spider | Shocker | Shriek | Swarm | Dracula | Spider-Slayers (Kaine) | Absorbing Man | Abomination | Annihilus | Arcade | Attuma | Awesome Android | Blastaar | Blizzard | Boomerang | Chitauri | Deadpool | Destroyer | Doctor Doom | Dormammu | Skurge | Enforcers (Montana, Fancy Dan, Ox) | Frost Giants | Grizzly | Hammerhead | Jack O'Lantern | Korvac | The Leader | Living Laser | Man-Wolf | Maximus | Melter | Mesmero | M.O.D.O.K. | Molten Man | Mister Negative | Mysterio | Nightmare | Norma Osborn | Phalanx | Sabretooth | Toad | Ulik | Whirlwind | Wrecker | Piledriver | Thunderball | Ymir | Zodiac | Scorpio | Zzzax | J. Jonah Jameson

Spider-Man (2017)
Symbiotes (Venom, Scream, Scorn and Mania) | Dark Goblin | Hobgoblin | Doctor Octopus | Vulture/Goblin King | Alistair Smythe | Rhino | Jackal | Hammerhead | Electro | A.I.M. (M.O.D.O.K.) | Spider-Slayers | Lizard | Tinkerer | Swarm | Scorpion | Sinister Six | Kraven the Hunter | Man-Wolf | Silver Sable | Beetle | Spot | Prowler | Molten Man | Mister Negative | Chameleon | HYDRA (Crossbones and Arnim Zola) | Black Cat | Ghost | Blizzard | Absorbing Man | Crimson Dynamo | Overdrive | Mysterio | Jack O'Lantern | Paladin | Puma | Shocker | Living Brain | Sandman | Technovore | Baron Mordo | Knull | J. Jonah Jameson

Video Games
Spider-Man: Return of the Sinister Six: Sinister Six (Doctor Octopus, Electro, Hobgoblin, Mysterio, Sandman and Vulture)
Spider-Man and Venom: Maximum Carnage: Carnage | Shriek | Doppelganger | Demogoblin | Carrion
Spider-Man and Venom: Separation Anxiety: The Jury | Sentry | Ramshot | Screech | Bomblast | Firearm | Wysper | Life Foundation | Symbiotes (Carnage | Riot | Lasher | Agony | Scream)
Spider-Man (2000): Doctor Octopus | Symbiotes | (Carnage) | Jade Syndicate | Monster Ock | Scorpion | Rhino | Mysterio
Spider-Man 2: Enter Electro: Electro | Beetle | Hammerhead | Lizard |Sandman | Shocker
Spider-Man (2002): Green Goblin | Shocker | Vulture | Spider-Slayers | Scorpion | Kraven the Hunter | Dennis Carradine | Harry Osborn | J. Jonah Jameson
Spider-Man 2: Doctor Octopus | Harry Osborn | Rhino | Mysterio | Shocker | Puma | Black Cat | Vulture | Calypso | J. Jonah Jameson
Ultimate Spider-Man: Bolivar Trask | Venom | Vulture | Silver Sable | Shocker | R.H.I.N.O. | Electro | Beetle | Green Goblin | Sandman | Carnage
Spider-Man 3: Venom | Sandman | New Goblin | Lizard | Scorpion | Kraven the Hunter | Calypso | Kingpin | Rhino | Morbius | Shriek | H-Bombers (Mad Bomber) | J. Jonah Jameson
Spider-Man: Web of Shadows: Spider-Man | Venom | Kingpin | Black Cat | Vulture | Electro | Tinkerer | Rhino
Spider-Man: Shattered Dimensions: Mysterio | Kraven the Hunter | Hammerhead | Hobgoblin | Electro | Sandman | Vulture | Scorpion | Deadpool | Juggernaut | Silver Sable | Goblin | Serena Patel | Carnage
Spider-Man: Edge of Time: Peter Parker | Atrocity | Walker Sloan
The Amazing Spider-Man: Spider-Slayers (Alistair Smythe) | Lizard | Rhino | Vermin | Scorpion | Felicia Hardy | Iguana | Nattie
The Amazing Spider-Man 2: Carnage | Kingpin | Green Goblin | Shocker | Kraven the Hunter | Black Cat | Electro | Chameleon | Norman Osborn | Cash Register Thief
Marvel's Spider-Man: Sinister Six (Doctor Octopus, Mister Negative, Electro, Vulture, Rhino and Scorpion) | Inner Demons | Norman Osborn | Silver Sable | Kingpin | Shocker | Tombstone | Taskmaster | Black Cat | Screwball | Hammerhead | Walter Hardy | Yuriko Watanabe
Marvel's Spider-Man: Miles Morales: Roxxon Energy Corporation (Simon Krieger) | The Underground (Tinkerer) | Prowler | Rhino | Kingpin | Norman Osborn | Doctor Octopus | Vulture

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