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I am as far beyond mutants as they are beyond you. I am eternal.
~ Apocalypse to Graydon Creed calling him a mutant.
Evil? I am not malevolent. I simply am. Which soon will be more than I can say for you.
~ Apocalypse to Cable regarding his "evil".

En Sabah Nur, or better known as Apocalypse, is one of the main antagonists of X-Men: The Animated Series. He is an ancient and extremely powerful mutant whose ultimate goal is to rule the entire planet and remake it in his own image.

He was voiced by the late John Colicos and by James Blendick after John's passing.

Biography

Stating that he knows more of this world than we dared dream, his ultimate goal is to destroy the current world so a new world could be created in his image.

He created a device which would turn mutants into his Horsemen. Eventually the X-Men defeat this attempt. Apocalypse eventually in the future realized that the battle of good vs. evil could never be seemingly won upon facing Cable. In their battle Apocalypse stole a device that would allow him to travel time itself. Apocalypse attempted to go back into the past to eliminate the most powerful psychics only to end up in the center of all time known as the Axis of Time.

There Apocalypse spent centuries learning of the Axis' power where he found he could sacrifice the psychics which would cause time to collapse on itself due to their vast powers and all them dying simultaneously in the Axis effecting the time stream. Apocalypse realized that the Axis and those inside would not only survive but they'd be able to then recreate reality as they saw fit. Recruiting several mutants only letting Mister Sinister and few know the truth. Eventually the X-Men find the secret of Apocalypse's immortality (a device that rejuvenated him every century) and plot to destroy it when it was fist created. With Cable's help and new time machine they succeed but Apocalypse isn't effected since in the Axis he doesn't need the device to recharge him and being outside of time he won't be effected by those events.

Ultimately Magneto and the X-Men are able rescue the psychics before Apocalypse can sacrifice them. After his plan failed, the psychics used their combined might to banish Apocalypse to the astral plane.

Unknown to all Apocalypse while in the Axis saved Fabian Cortez just in case of such an event. From the astral plane Apocalypse demanded Cortez find him a new body so he may transform it into an exact copy of his original to return to Earth. After Cortez failed to find one, Apocalypse used Cortez’s own body and returned to Earth to continue his mad dream.

Quotes

I am the rocks of the eternal shore... Crash against me and be broken.
~ Apocalypse to the X-Men.
You have travelled over 50 centuries of time to stop me. When will you learn it cannot be done?
~ Apocalypse to Cable.
Beast, how many peoples have dreamed of my end? You are no closer than the Babylonians with their swords and fire sticks! You really believed I was not invincible?
~ Apocalypse to Beast.
Spare me your petty judgements. They sprain from a brain too meager to comprehend my reality. Now taste the power of Apocalypse!
~ Apocalypse to Magneto and Mystique.
There exists no freedom from me; there is only freedom through me.
~ Apocalypse while battling the X-Men.
Magneto: [to Wolverine] I'm going after Apocalypse.
Apocalypse: Do what you will. For I fear no one.
~ Apocalypse, before beating Magneto with one blast.
Watch me and tremble... for I bring the purity of oblivion!
You only delay the inevitable! I who am eternal can never be defeated. Exterminate the vermin!
I know more of this world than you can even dream. That is why I must destroy it!


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Comics
Abomination | Absorbing Man | Adversary | Ahab | A.I.M. | Annihilus | Apocalypse | Arcade | Archangel | Arnim Zola | Avalanche | Awesome Android | Azazel | Badoon | Bastion | Baron Wolfgang von Strucker | Batroc | Belasco | Beyonder | Black Box | Blastaar | Blood Brothers | Bolivar Trask | Blob | Brotherhood of Evil Mutants | Bullseye | Cameron Hodge | Cassandra Nova | Children of the Vault | Clan Akkaba | Count Nefaria | Crossbones | Dark Avengers | Dark Beast | Dark Phoenix | Dark X-Men | Deadpool | Demon Bear | Dracula | Egghead | Emma Frost | Exodus | Fenris | Freedom Force | Friends of Humanity | Galactus | Graydon Creed | Hand | Hela | Hellfire Club | High Evolutionary | Hobgoblin | Holocaust | Horsemen of Apocalypse | HYDRA | Impossible Man | Juggernaut | Kang | Kid Omega | Kingpin | Klaw | Krakoa | Kraven | Lady Deathstrike | Legion | Leper Queen | Lilith | Living Monolith | Lizard | Loki | Madame Viper | Madelyne Pryor | Magneto | Magus | Malekith the Accursed | Mandarin | Marrow | Masters of Evil | Master Mold | Maximus | Mesmero | Mikhail Rasputin | Mister Jip | Mister Negative | Mister Sinister | Mojo | Mole Man | Morlocks | Moses Magnum | Mutant Response Division | Mystique | Mysterio | N'Astirh | Namor | Nanny | Nekra | Neo | Nimrod | Nitro | Norman Osborn | Obnoxio the Clown | Omega Gang | Omega Red | Onslaught | Orphan-Maker | Ozymandias | Pandemonia | Phalanx | Pilgrimm | Predator X | Proteus | Psycho-Man | Punisher (Earth-95216) | Purifiers | Pyro | Quicksilver | Reavers | Red Ghost | Red Skull | Reverend Craig | Rhino | Right | Rogue | Sabretooth | Sat-Yr-9 | Sauron | Savage Land Mutates | Scarlet Witch | Sebastian Shaw | Selene Gallio | Sentinels | Serpent Society | Shadow King | Shadow Xavier | Shocker | Silver Sable | Silver Samurai | Simon Trask | Skrulls | Spiral | Stranger | Stryfe | Stephen Lang | Sublime | Sugarman | Super-Adaptoid | Supreme Intelligence | Thanos | Tinkerer | Toad | Trevor Fitzroy | Typhoid Mary | Tyrannus | Unus | Vulcan | Vulture | Wendigo | Whiplash | Whirlwind | White Rabbit | William Stryker | Xemnu | Xorn

Movies
X-Men: Brotherhood of Mutants (Magneto, Mystique, Sabretooth & Toad) | Pyro
X2: William Stryker Jr. | Lady Deathstrike | Jason Stryker | Brotherhood of Mutants (Magneto, Mystique & Pyro)
X-Men: The Last Stand: Brotherhood of Mutants (Magneto, Dark Phoenix, Pyro, Juggernaut, Multiple Man & Mystique) | Omega Gang (Callisto, Psylocke, Quill, Arclight, Avalanche, Spike, Glob Herman & Phat) | Archangel
X-Men: First Class: Hellfire Club (Sebastian Shaw, Emma Frost, Azazel, Angel Salvadore & Riptide) | William Stryker Sr. | Magneto | Mystique
X-Men: Days of Future Past: Trask Industries (Bolivar Trask, William Stryker Jr. & Sentinels) | Magneto | Mystique | Toad | Horsemen of Apocalypse (Apocalypse)
X-Men: Apocalypse: Ashir En Sabah Nur/Horsemen of Apocalypse (Apocalypse, Magneto, Psylocke & Archangel) | Dark Phoenix | Mystique | William Stryker Jr.
X-Men: Dark Phoenix: Dark Phoenix | D'Bari (Vuk & Jones) | Brotherhood of Mutants (Magneto & Selene Gallio) | Mystique
The New Mutants: Essex Corp (Cecilia Reyes) | Demon Bear | Reverend Craig | Smiley Men

Television
X-Men (1992): Magneto | Sentinels | Sabretooth | Juggernaut | Apocalypse | Mesmero | Horsemen of Apocalypse | Mister Sinister | Omega Red | Brotherhood of Mutants (Mystique, Avalanche, Blob & Pyro) | Dark Phoenix | Master Mold | Bolivar Trask | Silver Samurai | Hellfire Club (Sebastian Shaw, Harry Leland, Jason Wyngarde, Donald Pierce & Emma Frost) | Reavers (Bonebreaker & Lady Deathstrike) | Supreme Intelligence | D'Ken Neramani | Deathbird | Graydon Creed | Red Skull | Silver Samurai | High Evolutionary | Phalanx
X-Men: Evolution: Magneto | Brotherhood of Mutants (Mystique, Avalanche, Toad, Blob, Quicksilver & Scarlet Witch) | Pyro | Mastermind | HYDRA (Madame Viper & Omega Red) | David Haller | Juggernaut | Bolivar Trask | Sentinels | Apocalypse | Horsemen of Apocalypse | Mesmero | Destiny
Wolverine and the X-Men: Brotherhood of Mutants (Magneto, Mystique, Scarlet Witch, Juggernaut, Quicksilver, Avalanche, Blob, Pyro & Toad) | Dark Phoenix | Bolivar Trask | Sentinels | Sabretooth | Mutant Response Division (Colonel Moss) | Shadow King | Hellfire Club (Sebastian Shaw, Donald Pierce, Harry Leland, Selene Gallio, Emma Frost & Stepford Cuckoos) | Master Mold | Silver Samurai

See Also
Deadpool Villains | X-Men Movie Villains | Wolverine Villains