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Blast Off is a devious Combaticon and an antagonist that appears throughout the Transformers franchise.
He was voiced by Milt Jamin in the original cartoon and Keith Silverstein in Fall of Cybertron.
Although Blast Off appears to be a cruel and ruthless opponent to the Autobots and a snob to his fellow Combaticons, he is in reality somewhat lonely as his missions in space shuttle mode leave him feeling isolated.
Fall of Cybertron
After Megatron was killed in battle, the Autobots came into possession of a large amount of energon. As such, Starscream tasked the Combaticons with diverting the transport by destroying a bridge. Vortex and Blast Off were sent to clear a short cut to allow Brawl to take a drop ship through. Blast Off went through first, drawing out Autobot mines for Vortex to destroy. Once they got through the ruins, the Autobots closed some huge shutters, so Blast Off went ahead, leaving Vortex behind to fight all the Autobots by himself. Once the bridge was down and Swindle brought the transport to a halt, the Combaticons combined into Bruticus and smashed through the rest of its defenses. Unfortunately the damage they did resulted in the transport crashing. Starscream was not very pleased at this "insubordination" and had them all arrested.
Blast Off and the Combaticons were later freed once Megatron was resurrected and retook his leadership. They were aboard the Nemesis as it pursued the Ark and Blast Off took part in the assault on the Autobot ship's engines as part of Bruticus. The giant demolished many Autobots before he was taken down by the combined efforts of Jazz and the Aerialbots before floating free of the Ark and into a mysterious black-hole along with everyone else.