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Brundlefly is an artificial creation as a result of a scientific experiment gone wrong in which Seth Brundle, oblivious to the presence of a common housefly in one of the Telepods, merges his DNA with the fly due to a programming flaw. Soon afterwards Brundle's hybrid DNA spliced with that of a fly initiates a slow and hideous metamorphosis into half man-fly creature with grotesque asymmetrical features; what is now known as Brundlefly.