Artificial Intelligences, or A.I.s for short are usually beings with a non-biological and inorganic form of self-awareness. They can be either technology-based (from programs or viruses and so on inhabiting a processor and/mechanical husk), magic-based (sentient mystical constructs such as golems or objects endowed with varying degree of sentience via. advanced spells), or combination of both.

Such villains are not always in mechanized forms but still living beings in their own rights. In fiction, they are usually created by biological entities but rebel against their creators. Sometimes these computers and their programs aren't evil but doing what they were programmed for (i.e. AUTO).

By definition, most of these count as Genderless regardless of the form(s) they take.

Types of A.I.s

• Robots: These are machines, especially ones programmable by biological lifeforms capable of carrying out a complex series of actions thanks to the Programs bringing them to life. Depending on how they are made they can be evil from the start, good friends to and assistants for their Creators, sentient or emotionless before becoming self-aware, mechanical lifeforms among which some became benevolent or hostile (i.e. Decepticons), etc.
• Sentient Programs: Flexible and rational Programs that perceive the environment and take actions to maximize their chances of success (i.e. Ultron, P.A.L.). They are even capable of mimicking cognitive functions associated with biological minds such as learning and problem-solving. Though many inhabit supercomputers instead of robotic bodies they are intended to manage complexities such as security, aid, warfare, etc. They can be evil from the start where they are Partners in Crime or turn when their controllers attempt to deactivate it, because of paranoia or heartless decisions that others are inferior and only worthy of extermination.
• Artificial & Synthetic Lifeforms/Foreign & Reconstructed Donors: Created by those such as God Wannabes and Immortality Seekers these types are Sentient Weapons and/or Possessed Objects carrying out specific tasks (i.e. Shadow the Hedgehog, the Etherious). This also includes Golems and the Mechanically Modified or Bio-Engineered, especially if they were produced from scratch. In some cases, they started out as different beings entirely before being enhanced and augmented.
• Organisms turned AIs: Humans, aliens, and other formerly living organisms that transferred their consciousness into machines (i.e Arnim Zola, and his MCU counterpart).