He was also known as James McCullen XXIV the buisnessman of M.A.R.S. Industries and the reason why he wears a metal mask is back in the old days of the McCullen family tree. One of his ancestors, James McCullen was a criminal for thieving and witchcraft and he was sentenced not to death, but to wear a metal mask for all eternity never to show his unmasked face again.
G.I. Joe: An American Hero
In the series, Destro is a secondary antagonist in the first season and a major antagonist in the second season. He shown to have a strange but contemptuous relationship with Cobra Commander, as he's open to express his disdain towards the Commander's failures, though the Commander tolerates this as Destro is the only member who can make doomsday devices for COBRA's ambitions. He even conspired with Dr. Mindbender and Tomax & Xamot to create Serpentor to act as COBRA's new leader, serving as his loyal right-hand man. He also grew a relationship with Baroness, often engaging into romance.
G.I. Joe: The Movie
In the movie, Destro soon learned that Golobulus of Cobra-la is the being responsible for the founding of COBRA and the creation of Serpentor, quickly turning against the Cobra Commander once again. He is last seen fighting against the Joes, but later escaped from the explosion that destroyed Cobra-La.
G.I. Joe (DiC)
In the DiC series, Destro grew into a relationship with Zarana, inciting a jealous Baroness to bring Cobra Commander back in power. Upon learning of this, Destro dumps Zarana and betrayed Serpentor to renew his alliance with Cobra Commander. Despite this, their plans against G.I. Joe never went into fruition, much to both Cobra Commander and Destro's dismay.
G.I. Joe: Resolute
In this miniseries, Destro is seen helping Baroness taking a group of scientists hostage until several Joes come by to rescue the scientists, much to both Destro and Baroness' dismay.
G.I. Joe: Renegades
Destro is seen as a middle-age businessman, serving as a CEO of MARS Industries in league with COBRA. Despite this, he is shown to be discomforted in working with Dr. Mindbender (due to the latter's immoral experiments). To that end, he leaked several info about Mindbender's project to the Joes, but Mindbender soon learns about this and reports Destro to Cobra Commander, who places a robotic mask as punishment for his betrayal.
In the end of the series, Destro is seen attacking the Joes with a prototype tank, though they foiled this by setting missile on the tank. It is unknown if Destro survived the explosion or not.
- Main article: Destro (G.I. Joe Film Series)
G.I. Joe: Renegades
G.I. Joe: Retaliation