Dominic Sanatori was Lionel Luthor's assistant and a recurring antagonist in the WB TV series Smallville, appearing in Seasons One and Two.
Dominic was jealous of Lex Luthor and wanted to take over LuthorCorp. He first arrived in Smallville under Lionel's orders and visited Lex Luthor at his mansion to discuss the company's profits. The company was performing twenty percent below projections, so Lionel wanted Lex to cut the work force, but Lex planned to increase it in a bold move aimed to put his competitors on the run. Lex was rude to Dominic, calling him a drone, and told him to go back to his father and inform him of what his plan was.
At the Luthor Mansion, Dominic Sanatori arrived ostensibly to perform an audit. Lex made it clear that Dominic was not wanted there. Dominic stated he was there to investigate several financial expenditures, including Lex's investigation into the car crash. Sanatori then went to the Kent Farm and asked Jonathan Kent if he had any idea why Lex spent so much money researching the car crash and the Kent family. Jonathan doesn’t know why, but he wasn't happy to know that Lex has been prying into their lives. The following night, Dominic met with Lex at the Luthor Mansion to further continue his investigation. Lex drugged Dominic, giving him spiked brandy. The next morning Lex drove back to Metropolis with Dominic bound and gagged in the trunk of his car. He met his father in an alley and showed him Dominic in the trunk. Lex tells his dad not to send any more drones to bother him or the Kents. His father actually seemed proud of how Lex handled Sanatori.