He was portrayed by Danny Trejo.
Meeting Xander Cage
According to the NSA, El Jefe was known to run a Colombian drug cartel with vast military resources by his side. As such, Augustus Gibbons decides to send in sports enthusiast Xander Cage as part of his training to become a new xXx agent.
As part of the field test, Cage, along with several prisoners, were sent to El Jefe's drug plantation, where several of El Jefe's soldiers arrive to the scene and detain them inside the warehouse. Upon hearing of the prisoners' arrival, El Jefe attempts to torture them for information. At first, Xander believes the interrogation and the field test to be fake (due to his first field test in stopping a staged diner robbery), but realizes that it's real after sniffing the blood on El Jefe's machete.
DeathThinking fast, Xander manages to free himself and beat up El Jefe and several of his men, just as the U.S. Army arrives to destroy the plantation. Upon witnessing the arrival of the U.S. Army, El Jefe tries to escape on an SUV, but one of the U.S. Army helicopters blows it up, killing him and his men inside. The rest of El Jefe's men were later detained while Xander decides to take on his first official mission to spy on Yorgi Azar Zimin of Anarchy 99 and foil his plan of bringing worldwide anarchy.