Francesco was portrayed by Francesco Arca, and Marco was portrayed by Matteo Taranto.
Following the death of Marco Sciarra, both thugs were briefly seen along with Blofeld attending Sciarra's funeral while serving as bodyguards for his widow Lucia. They are unaware that Bond (the man responsible for the death of Sciarra) is attending the funeral behind the shadows.
After the funeral is over, Francesco and Marco escorted Lucia back to her home. Needless to say, it was revealed that they were ordered by Blofeld to assassinate Lucia to cover their tracks and tie up loose ends. As such, Lucia is forced to walk outside into the backyard patio, where she closes her eyes as Francesco and Marco wield out their guns to kill her on the spot. Fortunately, Bond arrives to the rescue by shooting down Francesco and Marco. Lucia seems ungrateful at first as she knows that Blofeld will be on to Bond's tracks for this, but relents by telling Bond of the incoming SPECTRE meeting in Rome before being placed into protective custody by the CIA.