Suck fist, Dr. Dork!
~ Francine to Lisa Simpson

Francine Rhenquist is a bully and the main antagonist in The Simpsons episode, Bye Bye Nerdie.

She was voiced by Kathy Griffin


Being a new student at Springfield Elementary, other children consider Francine as a shy and withdrawn girl and they soon start gossiping her. However, Lisa, who feels sympathy to the new student, attempts to befriend her, only to be socked in the eye by Francine.

This incident doesn't discourage Lisa at all and she tries to befriend Francine once again. However, it ends up with Francine biting Lisa's beloved doll's head off and locking her in her own locker. Soon after, Francine becomes Lisa's (and the other nerds') worst nightmare.

When Nelson Muntz and other bullies deny to help Lisa because they don't do girls, Lisa decides to find another way. She notices Francine bullies only nerds and leaves alone the rest of the students just like Bart. As the research continues, Lisa slowly realizes Francine can smell pheromones nerds give off and which lead her to attack them.

Although being beaten up by Francine during the research, Lisa eventually manages to isolate the chemical which is emitted by every nerd, and thus create some sort of a bully repellent. With a little help from Francine's parents who are able to lock her in the cage, Lisa can demonstrate her repellent in front of scientists. Once Lisa applies her repellent on her, Francine stops trying to attack her and just stands in front of Lisa, looking puzzled around. The scientists are excited by Lisa's experiment, until Francine smells their own pheromones and starts attacking the scientists.


               The Simpsons Logo.svg Villains

Springfield Republican Party
Mr. Burns | Birch Barlow | Lindsey Naegle | Blue-Haired Lawyer | Waylon Smithers

Terwilliger Family
Cecil Terwilliger | Dame Judith Underdunk | Francesca Terwilliger | Gino Terwilliger | Robert Terwilliger Jr. | Robert Terwilliger Sr.

Springfield Mafia
Fat Tony | Fit Tony

Environmental Protection Agency
Russ Cargill

Globex Corporation
Hank Scorpio | Miss Goodthighs

Recurring Characters
Agnes Skinner | Artie Ziff | Baby Gerald | Constance Harm | Dolph Starbeam | God | Hans Sprungfeld | Herman Hermann | Itchy | Jessica Lovejoy | Jimbo Jones | Kearney Zzyzwicz | Matt Groening | Mr. Largo | Nelson Muntz | Patty & Selma Bouvier | Senator Mendoza | Snake Jailbird | Space Mutants | Wainwright Montgomery Burns Gina Vendetti |

Treehouse of Horror
Bart (Fly) | Count Burns | Gremlin | Groundskeeper Willie | Homer's Clones | Hugo Simpson II | Jonathan Frink Sr. | Kang and Kodos | Killer Toupée | King Snorky | Lard Lad | Muttonchop Murderer | Ned Flanders | Seymour Skinner | The Blob | The Devil | The Grand Pumpkin | Witch Marge

Guest Star Characters
Simon Cowell | Will Wright

Other Characters
Adil Hoxha | Adolf Hitler | Andy Hamilton | Bart Simpson's Creatures | Blue-Eyed Man | Bob Arnold | Captain Mordecai Barrows | Cesar & Ugolín | Cooder | Comic Book Guy (Brick Like Me) | Devan & Quenley Woosterfield | Dexter Colt | Dwight Diddlehopper | Francine Rhenquist | Frank Grimes, Jr. | French Chef | Glamorous Godfrey | Howard K. Duff VIII | Ironfist Burns | Jack Crowley | Jack Lassen | Julia | Kindergarten Teacher | Larry Kidkill | Lucille Botzcowski | Lyle Lanley | Les Moore | Mav & Portia | Molloy | Movementarians | Mr. Dirt | Nigel Bakerbutcher | Officer Krackney | Professor Werner Von Brawn | Rex Banner | Robotic Richard Simmons | Shadow Knight | Stanley DeGroot | Stubborn Ape | The Leader | Jay G

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