He was portrayed by Joe Pantoliano, who also played Cypher Reagan in The Matrix, Ralph Cifaretto in The Sopranos, Gabe Ugliano in Percy Jackson and the Olympians: The Lightning Thief, Albert Arlington in Call of Duty: Black Ops II and Stickyfins Whiting in SpongeBob SquarePants.
Francis is first seen breaking out of Clatsop County Jail aided by his brother, then pours a trail of gasoline near the jail and lights it up to detonate it with a gunshot. Later that evening Francis together with the Lighthouse Lounge, an abandoned seaside restaurant. Two FBI agents come in there that night but are shot and killed by Francis and Jack.
Francis helps unload the first body to take it to their base. When he returns home he has a little argument with his brother only to find out that someone has been in their hiding place.
As they return to bring a second body to the club they find Chuck who is going to call the police and believed that their car belonged to whoever could help him and they take him for questioning. Francis discovers a doubloon in Chuck's pocket now believing that there is a cave system hidden under the Lighthouse Lounge, after which he locks it in the room with his brother Sloth so that he and his family can reach the Goonies to take all of the treasure. One-Eyed Willy.
On the way Francis joins the children on a tree that acts as a bridge, but being wet he slips and falls painfully between the legs on the tree, Jack also slips and gets hurt and is immobilized too, and soon a strong current arrives that overwhelms the two, but they still manage to cling to the rocks of the shore. When they get to Francis, he gets a punch from Data's boxing glove and they are forced to redo the lap.
As they stand up, Francis falls and then points the gun at Andy and Brand, but they escape just in time. The Brothers follow him, and Francis must drag Jake, who is too afraid to climb over a large gap in the floor.
Once at the lagoon and on Hell, they capture the Goonies. Data tries to confront them with his inventions, but fails. They take the Goonies to the deck to force them to give them everything they have in their pockets and throw them overboard, when Sloth and Chunk after escaping from the room arrive to rescue them.
Francis and Jack try to subdue Sloths, but the latter ties them up and dangles him from the mast of the ship as he confronts his mother before abandoning ship.
Later they are brought down by Mama Fratelli and the three plunder the ship, but they trigger a One-Eyed Willy trap and the ship begins to crumble. Sloth brings the Goonies to safety out of the cave and stays behind to rescue Francis and the other Kindred. Fortunately, Sloths goes out together with Francis, Jack and Mama safe and sound at Cauldron Point, where Sloths is reunited with the Goonies and Francis, Jack and Mama are arrested by the police.