Just like his father, Frankie aspired to become a fierce, ruthless, unpleasant, bloodthirsty, and carnivorous predator. He disapproves of Lenny's vegetarianism and would often mock him for it, but does love him like a brother. Don Lino, who too disapproves of Lenny's good nature, orders Frankie to show him the ropes of how to hunt like a shark, despite Frankie's objections.
Using a secluded area, Frankie spots a fish named Oscar (the protagonist of the film) being zapped by Ernie and Bernie as punishment for wasting money of a lost race for his boss Sykes. Frankie sends Lenny off to attack, forcing Ernie and Bernie to flee away. However, Lenny tries to stage into attack Oscar while letting the latter to swim free without Frankie noticing. However, this fails, and an annoyed Frankie starts chasing around Oscar, until for some unknown reason, an anchor drops on Frankie's head, fatally injuring him. As Lenny goes over to Frankie's side, Frankie dies from his wounds, and Lenny swims away out of fear and grief. This event is what led everyone to think that Oscar has killed Frankie and dubbing him as the "Sharkslayer", to which Oscar uses to rise up to the reef.
Frankie's death devastated everyone in the mob, including Don Lino and his wife. After Frankie's funeral, Don Lino angrily vowed to kill Oscar for this. However, in the end, Oscar finally confesses about the true circumstances about Frankie's death to Lino and everyone in the reef, and that Lenny ran away out of grief because of it. Giving his condolences to Frankie, Oscar states that it would be pointless for him and Lino to feud against each other, and that everyone in the reef loves Lenny for who he is, and that Lino needs to do the same like he did to Frankie. Knowing that Oscar is right, a remorseful Lino reconciles with Lenny by apologizing for his behavior, and agrees with Oscar to form a peace between the reef and the mob, much to everyone's delight.
Frankie slaps Lenny
Frankie eating with Lenny and Lino at the restaurant
Frankie with Lenny
Frankie's nervous breakdown.
Frankie dying in Lenny's fins
Lenny mourning for Frankie's death
Lenny feeling guilty of the death of his brother
Frankie being dropped off the burial site, and floating to the surface whilst being mourned by his parents.
Frankie is often thought to be the main antagonist of the film. This is not true as Frankie did not appear as much as the other villains.
At one point in the film, Frankie is seen eating some oyster shells in the restaurant, but real-life sharks eat meat.
Despite being an antagonist, Frankie is not completely evil as he was somewhat nice to Lenny before he died despite being mean to him. However, after that, Frankie hit him and insulted him by calling him a moron just before he dies.
Frankie's death drives most of the movie's plot.
Frankie is so far the only animated movie character to be voiced by Michael Imperioli.