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Gianna D'Antonio is the overarching antagonist in John Wick: Chapter 2. She is one of the leaders of the Italian Mafia and a member of the High Table, a council of crime bosses.
She was portrayed by Claudia Gerini.
While attending a party, Gianna met Akoni, who confronted her over the fact that she had forced several crime lords to give up their land to her by holding a knife to their throats. Gianna retorted by saying that she had instead held the knife up to their children, and that they were only supposed to watch.
Gianna later went to go put on more makeup. However, she was followed by John Wick, who had been tasked by her brother, Santino D'Antonio, with assassinating her. Gianna briefly talked with John Wick and asked him who had sent him. John informed her that her brother had made him kill her with the blood oath he had sworn to him.
Resigned to the fact she was going to die, Gianna opted to die her way, and slit her wrists while taking a bath. However, John put a bullet in her skull for good measure.