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The Gru's Organization are the main protagonists of Illumination's Despicable Me franchise. They are the most infamous supervillains organisation led by Felonious Gru in attempt to become the number 1# villain in the world. However, Vector took place and realised his life was overrated, and he began a new pair of family with Margo, Agnes and Edith as well as his wife, Lucy. They are the arch-nemesis of El Macho's Lair.

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           DespicableMeTitle Villains

Gru's Family and Servants
Felonious Gru | Minions (Purple Minions | Mel) | Dr. Nefario | Dru Gru | The Bald Terror | Cookie Robots

Villain Con Villains
Scarlet Overkill | Herb Overkill | Nelson Family | Glam Slammer | Dumo The Sumo | Frankie Fishlips | Mr. Spikey

Vicious 6
Wild Knuckles | Belle Bottom | Jean-Clawed | Svengeance | Stronghold | Nun-Chuck

Bank of Evil
Mr. Perkins | Victor "Vector" Perkins | Vector's Drones

El Macho's Lair
Eduardo "El Macho" Perez | Purple Minions | El Pollito

Balthazar Bratt's Lair
Balthazar Bratt (Evil Bratt) | Clive | Bratt Pack

Lycee Pas Bon School of Villainy
Maxime Le Mal | Valentina | Felonious Gru | Poppy Prescott | Principal Übelschlecht

Others
Miss Hattie | Wild Knuckles' Henchmen | Valerie Da Vinci | Melora | Cockroaches | Meena the Cookie Scout | The Villaintriloquist | Temple Guards | Jewel Thief

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