Itsuro Negishi is the synchronization partner of the Open Roidmude and a minor antagonist in Kamen Rider Drive.
A criminal involved with a series of robberies, Itsuro Negishi was synchronized with Roidmude 067 using a Cobra Neo-Viral, forming the Open Roidmude. The Fusion Advanced Roidmude was tasked by the Brain Roidmude with killing anyone associated with a robbery Negishi had performed in 2003. After killing three bank workers, Open attempted robbery at another bank in order to kill Tomoko Sannomaru but Kamen Rider Drive appeared to stop the robbery and forced Open to retreat. Itsuro later attempted to kill his former accomplice Maruya, but Kiriko, Drive and Chase stopped him.
The Open Roidmude's next move was to go after Yukari Karasawa, a young girl who Eisuke Tomari had protected 12 years ago. Open headed towards hospital she was at, but Shinnosuke got there first to take her to a safe haven. As they exit the hospital, Open attempts to attack Yukari but Shinnosuke shields her, causing her to remember what happened 12 years ago. Kamen Rider Chaser soon appears to assist Drive and the two Riders perform their Full Throttle finishers which separate Itsuro from 067 and kills 067. Shinnosuke interrogates Negishi about the robbery incident, but discovers that he had his memory wiped by Freeze.