Boys were always in love with Itsy Bitsy however after she was done with them she usually poisoned and killed them. She later joined the TWF as a member of the Sinistras and became the third in command and one of the deadliest fighters. Throughout the first three seasons she defeated most of her opponents but never made it to the championship. In the fourth season she messed up one of Bucks Gazillion's plans and he scolded her resulting in her quitting. She later joined up with Senator Skull and a few other Sinistras and over threw Bucks.
Her signature move is her web which she can shoot like a real spider. She uses this to trap and bring down her opponents.