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Call me LUPO: Delta Team squad leader.
~ Karena LesProux's introduction.

Karena LesProux, also known as LUPO, is one of the main protagonists of Resident Evil spin-off Resident Evil: Operation Raccoon City.

She was voiced by Nika Futterman, who also played Khan Maykr in Doom Eternal, and Vendra Prog in Ratchet & Clank: Into the Nexus.



LesProux raised her family on her own after retiring her position in French Special Forces, she was married to a violent man, whom she later killed when she saw her children being abused.

After she was acquitted of murder by a sympathetic judge, LesProux tried to raise her children as a single mother, a task she proved incapable of carrying out. Despite her efforts to assimilate into a civilian environment, LesProux's instincts as a soldier remained deeply embedded in her nature. Thus, she returned to work as a mercenary, selling her services to the highest bidder in order to take care of her children.

Prior to the T-Virus outbreak in Raccoon City, LesProux was recruited by the Umbrella Corporation to serve as the leader of the newly constituted U.S.S. Delta Team, informally known as "Wolfpack." Under the codename "Lupo," or "wolf" in Italian, she serves as an expert in assault tactics and weapons use, as well as the team leader.

Beginning of the Outbreak

Wolfpack was sent to aid HUNK's U.S.S. Alpha Team in infiltrating a Umbrella facility beneath Raccoon City, their objective is to retrieve a sample of G-Virus from Dr. William Birkin, who planned to sell it to the US Government. LUPO and her team fight the U.B.C.S. soldiers and military escorts during their way to Birkin. However Birkin injected the virus himself and mutated, slaughtered Alpha Team in no time, LUPO with her team was told by HUNK to evacuate while he gets the sample himself.

Encounter with Nicholai

After getting out to the underground passages of Raccoon City Hall, LUPO and her team was ordered to eradicate the evidence in there, during their way up there, they met U.B.C.S soldier Nicholai Ginovaef, whom later caught betraying his teammates through security cameras. Despite succeeded in destroying the evidence, Nicholai ambushed them with Lickers. Wolfpack managed to fight their way out, and LUPO led her team to Raccoon General Hospital for rendezvous, but they're once again thwarted by Nicholai and his traps. Nicholai, now in the possession of EMP charges, blew the hospital up with rigged charges before retreats to the park, Wolfpack escaped and retrieved two charges, with the last one on Nicholai. Wolfpack successfully retrieved the final charge with Nicholai running away, also destroying the generators.


           Resident Evil 2019 Logo.png Villains

Umbrella Corporation
Oswell E. Spencer | James Marcus | Albert Wesker (film series) | Sergei Vladimir | Dr. Alexander Isaacs (Clone)

William Birkin (2021) | Morpheus D. Duvall | Alexia Ashford (TDC incarnation) | Alexander Ashford | Vincent Goldman | Monica Stevens | Dr. Sam Isaacs | Alexander Slater | Dexter Whitlam

HUNK | Ada Wong | Brian Irons | Nemesis | Nicholai Ginovaef | Undertaker Units | Callos | UT Commander | Alfred Ashford | Jesse Alcorn | Rodrigo Juan Raval | Klaus | Tommy Nielsen | Daniel Fabron | Alex Wesker | Jack Krauser | Unnamed Umbrella Executive | Mr. Venk | USS Delta Team (LUPO | VECTOR) | Red Queen | Spence Parks | Timothy Cain | Commander Chu | Doc | Bennett Sinclair | Bad Rain | Jill Valentine (Film Series)

Los Iluminados
Osmund Saddler | Jack Krauser | Ramon Salazar | Bitores Mendez | Don Esteban | Las Plagas | Ganado | Verdugo

Albert Wesker | Excella Gionne | Ricardo Irving | Majini | Instigator Majini

Baker Family
Eveline | Jack Baker | Lucas Baker | Marguerite Baker | Molded

The Village and Four Houses
Mother Miranda

House Dimitrescu
Alcina Dimitrescu | Bela Dimitrescu | Cassandra Dimitrescu | Daniela Dimitrescu | Moroaicǎ

House Beneviento
Donna Beneviento | Living Dolls (Angie) | Baby

House Moreau
Salvatore Moreau

House Heisenberg
Karl Heisenberg | Soldats | Sturm

Uriaș | Uriaș Strǎjer | Vârcolacs

The 3rd Organization
Albert Wesker | Hive-Host Capture Force

Jack Norman

Morgan Lansdale | Jessica Sherawat | Neil Fisher

The Family
Derek Clifford Simmons

Carla Radames | Edonian Liberation Army | Glenn Arias | J'avo

WilPharma Corporation
Frederic Downing | Curtis Miller

Glenn Arias | Diego Gomez | Maria Gomez

The Connections
Eveline | Lucas Baker | Mother Miranda

Zombie Dogs | Lickers | Axeman

Nosferatu | Hunters | Lycans | Moroaicǎ | Las Plagas | Soldats | Verdugo | A-Virus | J'avo | Ustanak

Nemesis T-Type | Mr. X | T-A.L.O.S. | Ivans | T-078 | Unidentified T-Series

Albert Lester | Javier Hidalgo | Ron Davis | Svetlana Belikova | Bindi Bergara | Nanan Yoshihara | Mylène Beardsley | Kelly Thorndike | Todd Umbenhauer | Wade Boddington III | Secretary Wilson | Jason | Albert Wesker (2021)