The Killer Toupée is the main antagonist in The Simpsons episode "Treehouse of Horror IX" segment, "Hell Toupée".
Snake was arrested for smoking in the Kwik-E-Mart. He was then sentenced to be executed in accordance with the Three Strikes law. The first two strikes were burning down an orphanage and blowing up a bus full of Nuns (which he claims was self defense). Chief Wiggum pointed out that Apu, Moe, and Bart are all witnesses. Snake vows to kill them all. He was executed in the electric chair on the TV show World's Deadliest Executions, hosted by Ed McMahon. His body was then taken to the hospital for organ donations. Homer visits Dr. Nick Riviera to receive Snake's hair to cure his baldness. After the operation, Homer shows the hair to his family with Marge saying that if his fly wasn't open, he looks just like Roger Moore.
Later that night when Homer was sleeping, the hair plants its roots in Homer's brain. Snake's spirit within the hair was controlling his mind and Homer spoke with Snake's voice. He goes to the Kwik-E-Mart and murders Apu by stuffing him in the Squishee machine, drowning him. The next night, he goes to Moe's Tavern and rips out Moe's heart with a corkscrew.
Bart realizes that the two witnesses from the Kwik-E-Mart were killed and that he's next. Homer vows to protect him and barricades himself and Bart in his room. The hair took control of his mind, causing Homer to try to kill Bart with a sledgehammer. Bart begs for Homer to fight the hair controlling him. Homer was then forced to choose either Bart or having a "luscious head of hair". Ultimately, Homer rips the hair from his head and embraced his son. The hair fights back in an attempt to smother Bart in a way similar to the facehugger. Homer starts punching the hair, but he was also punching Bart in the face. Bart called Homer an idiot, and Homer started strangling him. Chief Wiggum and the police arrived with the intention of arresting Homer for Moe's murder (originally for Apu and Moe but since he couldn't pronounce Apu's last name, he settled for just Moe). Homer states that the hair was the true killer. The hair tries to escape, but the police shoot it dead. Maggie picks up the hair and puts it on her head as a cushion. Chief Wiggum states "now that's a bad hair day" with everyone laughing but Marge who reminds everyone that two people are dead. But then she gets the joke and laughs with everyone until the end of the segment.