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The Loco Syndicate is the minor antagonistic partnership in the video game Grand Theft Auto: San Andreas. It is a three-membered syndicate that deal drugs to San Andreas. They served as the primary antagonist in the San Fierro missions.
The Loco Syndicate's business is dealing drugs in San Fierro. They are the most powerful organization in San Fierro and control every illegal actions. The organization have three original member and a few allies;
He is a mysterious businessman and the leader of the Loco Syndicate. When Jizzy B. and T-Bone are died, Mike defected from the organization, later it is revealed Mike Toreno is a government agent.
- Main article: T-Bone Mendez
He is a gangster and the leader of the San Fierro Rifa. He organizes the gang businesses.
- Main article: Jizzy B.
He is the most powerful pimp of San Fierro. He organizes the prostitution businesses.
Although the gang are considered to be enemies with the protagonist, one of the members, Mike Toreno, is affiliated with CJ. Jizzy B and T-Bone Mendez were also affiliated with him for a short time. It should be noted though that CJ has worked with the syndicate for infiltration purposes only. After he worked for Jizzy and T-Bone to gain their trust, Carl killed them to disband the syndicate. Mike Toreno himself has defected from the syndicate so he is not a member anymore.
- "Loco" means "crazy" in Spanish.