After Uso Ewin was captured, Lupe had him taken to a mansion and placed in a bubble bath. She then got naked and entering the bath as well. She then interrogated Uso by dunking his head underwater, attempting to determine if he was a Newtype.
However, Uso managed to get out of the bubble bath and escape, evading Lupe's attempts to recapture him.
She later dies when she rams her Mobile Suit into Arbeo's Birknau just as it is taking off, killing them both.