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We were orphans. Little girls, all alone. Hydra gave us a home. Eight great houses. Twelve girls to a house. And in the end, the most determined... the most ambitious... the most aggressive... That girl would be the Viper. All it cost was everything. I have been married to a man I hated. I could not marry the man I loved. I betrayed him. And I was betrayed in turn. Then I was murdered. Death, welcome and well - deserved. But HYDRA, it seems, will never be done with me... To live, and die and live again.
~ Madame Viper
You dare speak to me of mercy?!
~ Madame Viper

Ophelia Sarkissian, better known as Madame Viper, Madame Hydra, or Viper, is an antagonist from Marvel Comics and one of the leaders of the terrorist organization known as HYDRA. She is an enemy of Captain America, the X-Men, Spider-Woman, and the Avengers.

Biography

Early Life

Ophelia Sarkissian was born to unnamed parents and was orphaned, and was eventually recruited into Hydra. She became the student of the Kraken, and became a well-respected agent of the organization, earning the title "Viper". She gained a position in Hydra's inner circle, became a mercenary for a time, and pupil of Seraph. Later on, Viper and Seraph rescued the mutant Wolverine from Sabretooth, and Seraph died of his wounds.

Early years

Taking the name Madame Hydra, she took control of their New York operations and frequently clashed with the super-soldier Captain America.[16] However, her identity was stolen by the Space Phantom, who turned her branch of Hydra into his own private army. Madame Hydra eventually returned from Limbo after the Phantom ceased using her form, but was on the outs with Hydra due to his actions.[17] She reorganized the then-defunct Serpent Squad, killing the original costumed criminal Viper, taking his alias.[18] Acquiring the ancient and powerful Serpent Crown artifact, she sought world domination but was again opposed by Captain America. Viper next organized her own terrorist cell and employed the mutant warrior the Silver Samurai as her bodyguard.[11]

Viper battled Spider-Woman when Drew stumbled onto one of Viper's plots during her career as a private investigator in San Francisco. Viper, under the influence of Morgan le Fey, believed herself to be Meriem Drew, Spider-Woman's mother. Morgan sought to use the Viper as a weapon against Spider-Woman and briefly replaced the Viper's right eye with a black orb capable of projecting others into a magical dimension. Hoping to unravel the mysteries of her origin, Spider-Woman tracked Viper down to confront her and was tossed into this dimension and seemingly forced to confront Chthon. The elder god wanted to use Spider-Woman to emerge on Earth, but Viper ultimately defied Chthon, with the help of the force of will of Spider-Woman, who resisted Chthon long enough for Viper to ultimately free herself from his thrall.[3] This entire scenario was later revealed to be false when Viper broke free of the hypnotic blocks placed in her mind by le Fey. She blamed Spider-Woman for this violation of her mind, and tried to seek revenge.[5]

Soon after, Viper and the Silver Samurai clashed with the New Mutants when they attempted to coerce the motorcycle stunt riding Team America into stealing the Cavorite crystal.[19] Later still, Viper, alongside numerous other snake-inspired costumed villains, infiltrated the criminal organization known as the Serpent Society with the intent of taking it over. She poisoned the water supply in Washington D.C., changing most of the residents into snake-like humans, including the President.[20]

Viper subsequently entered into a brief alliance with the murderous Red Skull. However, this alliance was short lived as the two criminals soon double-crossed each other.[9][21]

When the throne of Madripoor was left without an heir, Viper brainwashed many of the women closest to Wolverine in order for them to capture and bring him to her. She reminded him of his old debt to Seraph, their mutual mentor. Following his code of giri, or honorable debt, Wolverine agreed to marry the Viper. The Viper had gambled that Wolverine's respectability in Madripoor would enable her to seize the throne. She also used him, along with Sabretooth and Shadowcat, to foil both Hydra and the Hand's attempts to control the island. Soon after, the Viper was installed as the ruling princess of Madripoor.

Following an illegal bloodsport tournament hosted on the island, in which Wolverine was a participant at the Viper's request, the demonic ninja spirit Ogun attacked. After failing to possess Wolverine, Ogun possessed Viper. In order to exorcise the spirit, Wolverine seriously wounded Viper, and Ogun's spirit was dissipated. In return for ensuring she received medical treatment, Wolverine made the Viper agree to divorce him. During this time, the Viper must have had plastic surgery to repair her facial scarring, as she no longer bore scars on the right side of her face.

Her reign was subsequently challenged by the alien warlord Khan. Viper helped organize a resistance force against an attempted alien invasion of Earth which had made its beachhead in Madripoor. Viper ran afoul of the X-Men, and betrayed their leader, Storm, who was subsequently captured by the aliens. Ultimately, the invasion was repelled by the X-Men and the Avengers. Viper returned to ruling Madripoor.

When Tony Stark was head of S.H.I.E.L.D., he wanted Viper dethroned, but S.H.I.E.L.D. couldn't attack a sovereign state, so Tony had to go there himself. After seeing Viper in her palace, where both tried to outsmart each other, Viper ordered Roughhouse and Bloodscream to kill Iron Man, but they failed. Tony Stark then turned the public against Viper and helped Tyger Tiger to become the next ruler.

In Other Media

Film

Main article: Madame Viper (X-Men Movies)

Madame Viper is the secondary antagonist in the 2013 live-action film The Wolverine. She was portrayed by Svetlana Khodchenkova.

Television

Marvel Cinematic Universe

Main article: Aida

Madame Hydra appears in the live-action ABC TV series Marvel's Agents of S.H.I.E.L.D., set in the Marvel Cinematic Universe, in the Agents of HYDRA story arc in Season 4 as part of the "Framework" simulation. In the Framework alternate reality, she is the leader of HYDRA. She is portrayed by Mallory Jansen, who portrays Aida, seemingly as her alternate-reality counterpart.

X-Men: Evolution

Madame Hydra appears in the Season 4 episode "Target X" in the animated cartoon series X-Men: Evolution as the leader of HYDRA and the mastermind behind the creation of X-23. She is seemingly killed by X-23 while trying to escape from her in a hovering vehicle, with the child having placed explosives all around the interior; her fate is unknown, but she is presumed deceased.

Personality

Madame Viper is shown to be a completely aggressive, remorseless, schizophrenic, materialistic, cantankerous, egotistical, vindictive, impatient, paranoid, sadistic, brutal, mean, greedy, violent, uncaring, murderous, sociopathic, manipulative, unmerciful, iniquitous, selfish, cruel, rude, and evil woman whose lust for power and conquest rivals that of fellow Hydra leaders Red Skull and Baron Strucker. She can and will cross any moral line in the pursuit of her goals, and became one of the most wanted criminals in the world when she horribly mutated 8,000 people in Symkaria, which earned her a death sentence from that country.

Being a classic nihilist, Madame Viper is also completely intolerant of failure, and every agent who has ever failed her has been executed without delay. 

For all of her capacity for cruelty though Madame Viper is also driven, determined, cunning, and ambitious, and these traits mixed with her complete lack of redeeming qualities makes her a dangerous threat indeed.

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Movies
Captain America (1990): Red Skull | Valentina de Santis
Captain America: The First Avenger: HYDRA (Red Skull, Arnim Zola, Heinz Kruger, HYDRA Lieutenant & Velt) | Adolf Hitler | Roeder | Hutter | Schneider
Heroes United: Iron Man and Captain America: HYDRA (Red Skull & Taskmaster)
Captain America: The Winter Soldier: HYDRA/STRIKE (Alexander Pierce, Winter Soldier, Crossbones, Jack Rollins, Jasper Sitwell, Russo, Senator Stern, Arnim Zola, Wolfgang von Strucker, List, Scarlet Witch & Quicksilver) | Georges Batroc | Ferdinand Lopez | Gerald Durand
Captain America: Civil War: Helmut Zemo | Thunderbolt Ross | Winter Soldier | Scarlet Witch | HYDRA (Vasily Karpov, Josef & Winter Soldiers) | Hero Mercs (Crossbones)

           Wolverine-Logo-600x257.png Villains

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Movies
Hulk Vs. Wolverine: Professor Thorton | Deadpool | Lady Deathstrike | Sabretooth | Omega Red
X-Men Origins: Wolverine: William Stryker Jr. | Sabretooth | Deadpool | Agent Zero | Blob
The Wolverine: Silver Samurai | Madam Viper | Shingen Yashida | Noburo Mori | Magneto
Logan: Essex Corp (Zander Rice, Donald Pierce, X-24 & Reavers)

Television
Brotherhood of Mutants (Magneto, Mystique, Scarlet Witch, Juggernaut, Quicksilver, Avalanche, Blob, Pyro & Toad) | Dark Phoenix | Bolivar Trask | Sentinels | Sabretooth | Mutant Response Division (Colonel Moss) | Shadow King | Hellfire Club (Sebastian Shaw, Donald Pierce, Harry Leland, Selene Gallio, Emma Frost & Stepford Cuckoos) | Master Mold | Silver Samurai

Video Games
Black Cat | Brigade | Fault Zone | Hazmat | Johnny Ohm | Niles Van Roekel | Solara | The Wink | Vulture

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Comics
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Movies
X-Men: Brotherhood of Mutants (Magneto, Mystique, Sabretooth & Toad) | Pyro
X2: William Stryker Jr. | Lady Deathstrike | Jason Stryker | Brotherhood of Mutants (Magneto, Mystique & Pyro)
X-Men: The Last Stand: Brotherhood of Mutants (Magneto, Dark Phoenix, Pyro, Juggernaut, Multiple Man & Mystique) | Omega Gang (Callisto, Psylocke, Quill, Arclight, Avalanche, Spike, Glob Herman & Phat) | Archangel
X-Men: First Class: Hellfire Club (Sebastian Shaw, Emma Frost, Azazel, Angel Salvadore & Riptide) | William Stryker Sr. | Magneto | Mystique
X-Men: Days of Future Past: Trask Industries (Bolivar Trask, William Stryker Jr. & Sentinels) | Magneto | Mystique | Toad | Horsemen of Apocalypse (Apocalypse)
X-Men: Apocalypse: Ashir En Sabah Nur/Horsemen of Apocalypse (Apocalypse, Magneto, Psylocke & Archangel) | Dark Phoenix | Mystique | William Stryker Jr.
X-Men: Dark Phoenix: Dark Phoenix | D'Bari (Vuk & Jones) | Brotherhood of Mutants (Magneto & Selene Gallio) | Mystique
The New Mutants: Essex Corp (Cecilia Reyes) | Demon Bear | Reverend Craig | Smiley Men

Television
X-Men (1992): Magneto | Sentinels | Sabretooth | Juggernaut | Apocalypse | Mesmero | Horsemen of Apocalypse | Mister Sinister | Omega Red | Brotherhood of Mutants (Mystique, Avalanche, Blob & Pyro) | Dark Phoenix | Master Mold | Bolivar Trask | Silver Samurai | Hellfire Club (Sebastian Shaw, Harry Leland, Jason Wyngarde, Donald Pierce & Emma Frost) | Reavers (Bonebreaker & Lady Deathstrike) | Supreme Intelligence | D'Ken Neramani | Deathbird | Graydon Creed | Red Skull | Silver Samurai | High Evolutionary | Phalanx
X-Men: Evolution: Magneto | Brotherhood of Mutants (Mystique, Avalanche, Toad, Blob, Quicksilver & Scarlet Witch) | Pyro | Mastermind | HYDRA (Madame Viper & Omega Red) | David Haller | Juggernaut | Bolivar Trask | Sentinels | Apocalypse | Horsemen of Apocalypse | Mesmero | Destiny
Wolverine and the X-Men: Brotherhood of Mutants (Magneto, Mystique, Scarlet Witch, Juggernaut, Quicksilver, Avalanche, Blob, Pyro & Toad) | Dark Phoenix | Bolivar Trask | Sentinels | Sabretooth | Mutant Response Division (Colonel Moss) | Shadow King | Hellfire Club (Sebastian Shaw, Donald Pierce, Harry Leland, Selene Gallio, Emma Frost & Stepford Cuckoos) | Master Mold | Silver Samurai

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Abomination | Abominatrix | Absorbing Man | Adolf Hitler | Agony | A.I.M. | Air-Walker | Alkhema | Aleksander Lukin | Alistair Smythe | Amatsu-Mikaboshi | Amora | Annihilus | Ani-Men | Answer | Apocalypse | Arcade | Ares | Arnim Zola | Atlas | Attuma | Avalanche | Awesome Android | Badoon | Barracuda | Baron Blood | Baron Mordo | Baron Wolfgang von Strucker | Baron Zemo | Baron Zemo II | Basilisk | Batroc | Beetle | Beyonder | Black Knight | Blackout | Black Order | Black Cat | Black Talon | Black Widow | Blackie Drago | Blastaar | Blitzkrieg | Blizzard | Blob | Blood Brothers | Bombshell | Boomerang | Brothers Grimm | Brotherhood of Evil Mutants | Bullseye | Burglar | Bushmaster | Bushwacker | Cache | Carnage | Carrion | Calypso | Celestials | Centurion | Chameleon | Chance | Chemistro | Chester Goudal | Chitauri | Collector | Colonel Ross Whittaker | Commander Kraken | Constrictor | Corruptor | Count Nefaria | Cowled Commander | Crime-Master | Crimson Dynamo | Crimson Widow | Cristu Bulat | Crossbones | Crossfire | Daken | Damage | Daniel Whitehall | Dark Avengers | Dark Elves | Deadpool | Deathbird | Deathurge | Death Adder | Deke Wainscroft | Demogoblin | Diablo | Doctor Doom | Doctor Faustus | Doctor Octopus | Doctor Spectrum | Dormammu | Dracula | Dreadknight | Eddie Brock | Eel | Egghead | Ego the Living Planet | Electro | Elementals | Elements of Doom | Enclave | Enforcers | Equinox | Exodus | Ezekiel Stane | Fabian Cortez | Famine | Fin Fang Foom | Finn Cooley | Firelord | Fixer | Fold | Frost | Frost Giants | Frightful Four | Galactus | Gargantus | Garthan Saal | Ghost | Goliath | Gladiator | Godzilla | Grand Director | Grandmaster | Grant Ward | Graviton | Green Goblin (Norman Osborn, Harry Osborn) | Grey Goblin | Griffin | Grim Reaper | Grizzly | Growing Man | Grotesk | Hammerhead | Hand | Hazmat | Hela | Hera | Herr Kleiser | Heinz Kruger | High Evolutionary | Hitman | Hive | Horsemen of Apocalypse | Hobgoblin | Hydro-Man | HYDRA | Immortus | Impossible Man | Ironclad | Jackal | Jack O' Lantern | Jester | Jigsaw | Johnny Ohm | Jonas Hambleton | Jormungandr | Juggernaut | Justin Hammer | Kaine | Kang the Conqueror | Killer Shrike | King Cobra | Kingpin | Klaw | Knull | Korath the Pursuer | Korvac | Kraven the Hunter | Kree | Lady Deathstrike | The Leader | Lightmaster | Living Brain | Living Laser | Living Monolith | Lizard | Loki Laufeyson | Lucia Von Bardas | Ma Gnucci | Machinesmith | Mad Pharaoh | Madame Masque | Madame Viper | Madcap | Madelyne Pryor | Maelstrom | Maestro | Maginty | Magneto | Magus | The Maker | Malekith the Accursed | Man-Ape | Mandarin | Mandrill | Man-Spider | Man-Wolf | Master Man | Master Pandemonium | Masters of Evil | Masked Marauder | Maximus the Mad | Melter | Menace | Mentallo | Mercurio the 4-D Man | Mesmero | Mephisto | Mister Fear | Mister Hyde | Mister Negative | Mister Payback | Mister Sinister | M.O.D.A.M. | M.O.D.O.K. | Mojo | Molecule Man | Mole Man | Molten Man | Moonstone | Morbius the Living Vampire | Morgan le Fay | Moses Magnum | Mystique | Mysterio | Namor | Nebula | Nekra | Nicky Cavella | Nightmare | Nightshade | Niles Van Roekel | Nicky Cavella | Obadiah Stane | Omega Red | Onslaught | Overdrive | Owl | Paladin | Phalanx | Phil Urich | Piledriver | Pluto | Presence | Princess Python | Proctor | Psycho-Man | Puppet Master | Puma | Purple Man | Quasimodo | Quicksand | Radioactive Man | Ragnarok | Ramrod | Reavers | Red Ghost | Red Skull | Reverend Samuel Smith | Rhino | Rhino II | The Rose | Ringer | Ringmaster | Riot | Ronan the Accuser | Roxxon | Sabretooth | Sandman | Säurespritze | Sauron | Savage Land Mutates | Scarecrow | Scarlet Witch | Scorcher | Scorpion | Screaming Mimi | Sebastian Shaw | Secret Empire | Selene Gallio | Sentinels | Sentry 459 | Serpent Society | Shriek | Shocker | Shockwave | Sidewinder | Silver Sable | Sin | Sinister Six | Skaar | Skeleton Crew | Skrulls | Skurge | Slug | Space Phantom | Spider-Man Revenge Squad | Spider-Slayers | Spot | Squadron Sinister | Stranger | Street | Sunstroke | Superia | Super-Adaptoid | Super-Apes | Super Patriot | Super-Skrull | Supreme Intelligence | Superia | Surtur | Swarm | Swordsman | Symbiotes | Tarantula | Taskmaster | Technovore | Temugin | Ten Rings | Terminus | Thanos | Thunderball | Thunderbolts | Thunderbolt Ross | Thundersword | Tiger Shark | Tinkerer | Titania | Titanium Man | Toad | Tombstone | Trapster | Trick Shot | Terrax the Tamer | Typhoid Mary | Tyrannus | U-Foes | Ulik | Ultimus | Ultron | Unicorn | Universal Church of Truth | Vapor | Vector | Venom | Vermin | Vulture | Walrus | Warlord Krang | Whiplash | Whirlwind | White Rabbit | Will-O'-The-Wisp | Winter Soldier | Wizard | Wonder Man | Wrecker | Worthy | X-Ray | Yellow Claw | Ymir | Yon-Rogg | Zahnmörder | Zodiac | Zombie Giant-Man | Zombie Sentry | Zzzax

Television
The Avengers: United They Stand: Ultron | Kang the Conqueror | Swordsman | Ringmaster | Masters of Evil (Baron Zemo, & Whirlwind) | Attuma | Zodiac (Taurus & Scorpio) | Egghead | Scarlet Witch | Grim Reaper
The Super Hero Squad Show: Doctor Doom | Mole Man | Fin Fang Foom | Abomination | Wrecker | Thunderball | Piledriver | M.O.D.O.K. | Klaw | Toad | Melter | Dormammu | Sabretooth | Juggernaut | Pyro | Whirlwind | Zzzax | Enchantress | Baron Mordo | Punisher | Egghead | Ringmaster | Skrulls (Super-Skrull) | Trapster | Mystique | Impossible Man | The Leader | Mad Thinker | Skurge | Crimson Dynamo | Batroc the Leaper | Loki Laufeyson | Magneto | Quicksilver | Scarlet Witch | HYDRA (Red Skull , Arnim Zola & Baron Wolfgang von Strucker) | Galactus | Terrax the Tamer | Firelord | Stardust | Thanos | Kree | Ego the Living Planet | Grandmaster | Annihilus | Nebula | Ronan the Accuser | Nightmare | Ultron | Dark Surfer | Sentinels | Dracula | High Evolutionary
Avengers: Earth's Mightiest Heroes: HYDRA (Red Skull, Baron Von Strucker, Grim Reaper, Arnim Zola, Doughboy & Madame Viper) | Masters of Evil (Baron Zemo, Enchantress, Skurge, Chemistro, Abomination, Crimson Dynamo & Grey Gargoyle) | A.I.M. (M.O.D.O.K.) | Kree Empire (Supreme Intelligence, Colonel Yon-Rogg & Ronan the Accuser) | Absorbing Man | Klaw | Ultron | Wrecker | Thunderball | Piledriver | Red Hulk | Frost Giants (Loki Laufeyson & Ymir) | Technovore | Bi-Beast | The Leader | Whirlwind | Kang the Conqueror | Man-Ape | Malice | Mad Thinker | Mandrill | Graviton | Fenris Wolf | Lucia Von Bardas | Zzzax | Blizzard | Constrictor | Griffin | Living Laser | Whiplash | King Cobra | Magneto | Wendigo | Skrulls (Super-Skrull) | Malekith the Accursed | Hela | Doctor Doom | Surtur | Glenn Talbot | Winter Soldier | J. Jonah Jameson | Destroyer | Annihilus | Purple Man | Galactus | Firelord | Stardust | Terrax the Tamer
Avengers Assemble: HYDRA/A.I.M. (Red Skull, M.O.D.O.K., Blood Brothers, Grim Reaper, Crossbones & Baron Wolfgang von Strucker) | J. Jonah Jameson | Doctor Doom | Ulik | Impossible Man | Dracula | Hyperion | Wrecker | Thunderball | Piledriver | Destroyer | Loki Laufeyson | Chitauri | Justin Hammer | Mojo | Galactus | Ringmaster | Black Order (Thanos) | Hela | Winter Soldier | Nighthawk | Dormammu | Ultron | Roxxon Energy Corporation | Absorbing Man | Titania | Whirlwind | Fin Fang Foom | Masters of Evil (Baron Zemo, Beetle & Goliath) | Klaw | Ghost | A.I.M. (Kang the Conqueror, Whiplash & Spymaster) | Abomination | Kree Empire | Egghead | The Leader | Crimson Widow | Arnim Zola | Enchantress | Skurge | Typhoid Mary | Ares | Taskmaster | Doughboy | Ulik | Beyonder | Symbiotes | Morgan le Fey | Tiger Shark | Erik Killmonger | Man-Ape | Madame Masque | Kraven the Hunter | Vulture

Movies
Ultimate Avengers 1 & 2: Herr Kleiser | Chitauri
Next Avengers: Heroes of Tomorrow: Ultron
The Avengers: Loki Laufeyson | Chitauri (The Other & Leviathans) | HYDRA (Gideon Malick & Jasper Sitwell) | Georgi Luchkov | Thanos
Avengers: Age of Ultron: Ultron | Ultron Sentinels | HYDRA (Wolfgang von Strucker, List, Scarlet Witch & Quicksilver) | Ulysses Klaue | Madame B | Chitauri (Leviathans) | Thanos
Avengers: Infinity War: Black Order (Thanos, Ebony Maw, Proxima Midnight, Corvus Glaive, Cull Obsidian, Nebula, Outriders, Chitauri & Leviathans) | Red Skull | The Collector | Loki Laufeyson | Winter Soldier | M'Baku | Scarlet Witch | Thunderbolt Ross
Avengers: Endgame: Black Order (Thanos, Ebony Maw, Proxima Midnight, Corvus Glaive, Cull Obsidian, Nebula, Outriders, Sakaaran Mercenaries, Chitauri, Leviathans & Chitauri Gorillas) | HYDRA/STRIKE (Red Skull, Alexander Pierce, Crossbones, Jasper Sitwell & Jack Rollins) | Loki Laufeyson | Winter Soldier | M'Baku | Scarlet Witch | Kraglin Obfonteri | Dark Elves | Thunderbolt Ross | Akihiko

Video Games
Marvel's Avengers: M.O.D.O.K. | Monica Rappaccinni | Abomination | Taskmaster | Super-Adaptoid | Lyle Getz

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Everwraith | Lord Deathstrike | Silver Samurai | X the Unknowable | Madame Viper | Badgal | Whiplash | Crimson Cowl | Yandroth

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          508759 thumb.png Villains

Comics
Abomination | Absorbing Man | Agony | A.I.M. | Alistair Smythe | Annihilus | Answer | Arcade | Arnim Zola | Awesome Android | Baron Zemo II | Basilisk | Beetle | Beyonder | Black Cat | Blackie Drago | Blastaar | Blizzard | Blob | Bombshell | Boomerang | Brothers Grimm | Burglar | Bullseye | Bushwacker | Cadaverous | Calypso | Carlton Drake | Carnage | Carrion | Chameleon | Chance | Constrictor | Crime Master | Crossbones | Daemos | Dark Avengers | Deadpool | Demogoblin | Diablo | Doctor Doom | Doctor Faustus | Doctor Octopus | Doppelganger | Dormammu | Electro | Enforcers | Equinox | Fancy Dan | Firelord | Freak | Frightful Four | Ghost | Gog | Goliath | Grant Ward | Graviton | Green Goblin (Norman Osborn, Harry Osborn & Bart Hamilton) | Grey Goblin | Grizzly | Hammerhead | Hand | Hazmat | High Evolutionary | Hitman | Hobgoblin | Human Fly | Hybrid | HYDRA | Hydro-Man | Inheritors | Iguana | Jackal | Jack O' Lantern | Jigsaw | J. Jonah Jameson | Johnny Ohm | Jonas Harrow | Juggernaut | Justin Hammer | Kaine | Karn | Killer Shrike | King Cobra | Kingpin | Knull | Kraven the Hunter | Lasher | Lady Deathstrike | The Leader | Lightmaster | Living Brain | Living Laser | Lizard | Loki Laufeyson | Madame Masque | Madame Viper | Maestro | Magneto | Mandarin | Man-Spider | Man-Wolf | Mania | Masters of Evil | Menace | Mephisto | Mesmero | Mister Fear | Mister Hyde | Mister Negative | Mojo | Molten Man | Montana | Morbius | Morlun | Moses Magnum | Mysterio | Nekra | Nightmare | Niles Van Roekel | Nitro | Onslaught | Overdrive | Owl | Ox | Phil Urich | The Prowler | Psycho-Man | Puma | Punisher | Punisher (Earth-95126) | Ramrod | Raze | Red Ghost | Red Skull | Rhino | Rhino II | Richard Fisk | Ringer | Riot | The Rose | Roxxon Energy Corporation | Sabretooth | Sandman | Sauron | Scarecrow | Scorcher | Scorpion | Scorn | Scream | Sebastian Shaw | Secret Empire | Sentinels | Seth Youngblood | Shocker | Shriek | Silver Sable | Sinister Six | Skip | Skrulls | Solus | Patton Parnel | Spider-Man Revenge Squad | Spider-Slayers | Spot | Street | Super-Apes | Supercharger | Swarm | Symbiotes | Tarantula | Taskmaster | Terminus | Thunderball | Thunderbolts | Tinkerer | Titania | Titanium Man | Tombstone | Trapster | Tyrannus | Ultimatum | Ultron | Venom (Eddie Brock) | Vermin | Vulture | Walrus | Whiplash | White Rabbit | Whirlwind | Will-O'-The-Wisp | Wizard | Worthy | Wrecker | Zodiac | Zombie Spider-Man | Zombie Giant-Man

Movies
Spider-Man: Green Goblin | Dennis Carradine | Bank Robbers | Harry Osborn | J. Jonah Jameson
Spider-Man 2: Doctor Octopus | Harry Osborn | J. Jonah Jameson | Green Goblin
Spider-Man 3: Venom | Sandman | New Goblin | J. Jonah Jameson | Green Goblin | Dennis Carradine
The Amazing Spider-Man: Lizard | Gustav Fiers | Cash Register Thief | Norman Osborn
The Amazing Spider-Man 2: Electro | Green Goblin | Donald Menken | Rhino | Alistair Smythe | Ashley Kafka | Felica Hardy | Gustav Fiers | Norman Osborn
Spider-Man: Homecoming: Bestman Salvage (Vulture, Tinkerer, Shocker #1, Shocker #2 & Randy Vale) | Mac Gargan | Aaron Davis
Spider-Man: Into the Spider-Verse: Kingpin | Prowler | Doctor Octopus | Tombstone | Scorpion | Green Goblin | Vanessa Fisk | Richard Fisk
Spider-Man: Far From Home: Mysterio's Crew (Mysterio, William Ginter Riva, Victoria Snow, Gutes Guterman, Janice Lincoln, & Doug) | Elementals (Molten Man, Hydro-Man, Sandman, Cyclone & Elemental Fusion) | Skrulls (Talos) | Obadiah Stane | J. Jonah Jameson

Television
Spider-Man (1967)
Vulture | Green Goblin | Electro | Rhino | Mysterio | Doctor Octopus | Scorpion | Human Fly | Kingpin | Lizard | Spider-Slayer | Sandman | Dr. Matto Magneto | Enforcers (Cowboy & Ox) | Frederick Foswell | J. Jonah Jameson

Spider-Man (1981)
Doctor Doom | Kingpin | Doctor Octopus | Lizard | Black Cat | Sandman | Magneto | Mysterio | Ringmaster | Green Goblin | Sidewinder | Kraven the Hunter | Red Skull | Chameleon | Vulture | Hammerhead | Wizard

Spider-Man and His Amazing Friends
Green Goblin | Kraven the Hunter | Doctor Doom | Swarm | Chameleon | Electro | Brotherhood of Mutants (Magneto, Blob, Toad & Mastermind) | Mysterio | Loki Laufeyson | Ymir | Mordred | Kingpin | Doctor Faustus | Red Skull | Juggernaut | Shocker | Sandman | Dracula | Scorpion | Beetle | Doctor Octopus | A.I.M.

Spider-Man: The Animated Series
Kingpin | Green Goblin (Norman Osborn & Harry Osborn) | Doctor Octopus | Hobgoblin | Venom | Vanessa Fisk | Richard Fisk | Insidious Six (Scorpion, Rhino, Mysterio, Chameleon, Shocker & Vulture) | Black Cat | Lizard | Morbius | Spider-Carnage | Spider-Slayers (Alistair Smythe) | Carnage | Baron Mordo | Dormammu | Silver Sable | Hydro-Man | Prowler | Doctor Doom | Red Skull | Electro | Hammerhead | Tombstone | Kraven the Hunter | Calypso | Herbert Landon | Jackal | Spot | J. Jonah Jameson

Spider-Man: The New Animated Series
Harry Osborn | Electro | Kraven the Hunter | Turbo Jet | Kingpin | Lizard | Shikata | Silver Sable

The Spectacular Spider-Man
Green Goblin | Tombstone | Doctor Octopus | Hammerhead | Venom | Sinister Six (Rhino, Vulture, Electro, Sandman, Mysterio & Kraven the Hunter) | Chameleon | Tinkerer | Enforcers (Shocker, Ricochet & Ox) | Molten Man | Silver Sable | Harry Osborn | Lizard | J. Jonah Jameson | Black Cat | Miles Warren | Frederick Foswell | Calypso | Roderick Kingsley | Morris Bench | Cletus Kasady

Ultimate Spider-Man
Doctor Octopus | Green Goblin | Harry Osborn | Taskmaster | HYDRA (Arnim Zola, Crossbones, Morbius & Baron Mordo) | Sinister Six (Kraven the Hunter, Rhino, Electro, Scorpion, Vulture & Hydro-Man) | Batroc the Leaper | Beetle | Lizard | Frightful Four (Wizard, Trapster & Klaw) | Juggernaut | Sandman | Venom | Loki Laufeyson | The Collector | Grandmaster | Carnage | Wolf Spider | Shocker | Shriek | Swarm | Dracula | Spider-Slayers (Kaine) | Absorbing Man | Abomination | Annihilus | Arcade | Attuma | Awesome Android | Blastaar | Blizzard | Boomerang | Chitauri | Deadpool | Destroyer | Doctor Doom | Dormammu | Skurge | Enforcers (Montana, Fancy Dan, Ox) | Frost Giants | Grizzly | Hammerhead | Jack O'Lantern | Korvac | The Leader | Living Laser | Man-Wolf | Maximus | Melter | Mesmero | M.O.D.O.K. | Molten Man | Mister Negative | Mysterio | Nightmare | Norma Osborn | Phalanx | Sabretooth | Toad | Ulik | Whirlwind | Wrecker | Piledriver | Thunderball | Ymir | Zodiac | Scorpio | Zzzax | J. Jonah Jameson

Spider-Man (2017)
Symbiotes (Venom, Scream, Scorn & Mania) | Dark Goblin | Hobgoblin | Doctor Octopus | Vulture/Goblin King | Alistair Smythe | Rhino | Jackal | Hammerhead | Electro | A.I.M. (M.O.D.O.K.) | Spider-Slayers | Lizard | Tinkerer | Swarm | Scorpion | Sinister Six | Kraven the Hunter | Man-Wolf | Silver Sable | Beetle | Spot | Prowler | Molten Man | Mister Negative | Chameleon | HYDRA (Crossbones & Arnim Zola) | Black Cat | Ghost | Blizzard | Absorbing Man | Crimson Dynamo | Overdrive | Mysterio | Jack O'Lantern | Paladin | Puma | Shocker | Living Brain | Sandman | Technovore | Baron Mordo | Knull | J. Jonah Jameson

Video Games
Spider-Man: Return of the Sinister Six: Sinister Six (Doctor Octopus, Electro, Hobgoblin, Mysterio, Sandman & Vulture)
Spider-Man & Venom: Maximum Carnage: Carnage | Shriek | Doppelganger | Demogoblin | Carrion
Spider-Man & Venom: Separation Anxiety: The Jury | Sentry | Ramshot | Screech | Bomblast | Firearm | Wysper | Life Foundation | Symbiotes (Carnage | Riot | Lasher | Agony | Scream)
Spider-Man (2000): Doctor Octopus | Symbiotes | (Carnage) | Jade Syndicate | Monster Ock | Scorpion | Rhino | Mysterio
Spider-Man 2: Enter Electro: Electro | Beetle | Hammerhead | Lizard |Sandman | Shocker
Spider-Man (2002): Green Goblin | Shocker | Vulture | Spider-Slayers | Scorpion | Kraven the Hunter | Dennis Carradine | Harry Osborn | J. Jonah Jameson
Spider-Man 2: Doctor Octopus | Harry Osborn | Rhino | Mysterio | Shocker | Puma | Black Cat | Vulture | Calypso | J. Jonah Jameson
Ultimate Spider-Man: Bolivar Trask | Venom | Vulture | Silver Sable | Shocker | R.H.I.N.O. | Electro | Beetle | Green Goblin | Sandman | Carnage
Spider-Man 3: Venom | Sandman | New Goblin | Lizard | Scorpion | Kraven the Hunter | Calypso | Kingpin | Rhino | Morbius | Shriek | H-Bombers (Mad Bomber) | J. Jonah Jameson
Spider-Man: Web of Shadows: Spider-Man | Venom | Kingpin | Black Cat | Vulture | Electro | Tinkerer | Rhino
Spider-Man: Shattered Dimensions: Mysterio | Kraven the Hunter | Hammerhead | Hobgoblin | Electro | Sandman | Vulture | Scorpion | Deadpool | Juggernaut | Silver Sable | Goblin | Serena Patel | Carnage
Spider-Man: Edge of Time: Peter Parker | Atrocity
The Amazing Spider-Man: Spider-Slayers (Alistair Smythe) | Lizard | Rhino | Vermin | Scorpion | Felicia Hardy | Iguana | Nattie
The Amazing Spider-Man 2: Carnage | Kingpin | Green Goblin | Shocker | Kraven the Hunter | Black Cat | Electro | Chameleon | Norman Osborn | Cash Register Thief
Marvel's Spider-Man: Sinister Six (Doctor Octopus, Mister Negative, Electro, Vulture, Rhino & Scorpion) | Inner Demons | Norman Osborn | Silver Sable | Kingpin | Shocker | Tombstone | Taskmaster | Black Cat | Screwball | Hammerhead | Walter Hardy | Yuriko Watanabe
Marvel's Spider-Man: Miles Morales: Roxxon Energy Corporation (Simon Krieger) | The Underground (Tinkerer) | Prowler | Rhino | Kingpin | Norman Osborn | Doctor Octopus | Vulture

          IMG 20190517 160507.jpg Villains

Comics
Absorbing Man | Barracuda | Baron Zemo II | Batroc | Belasco | Black Widow | Bullseye | Bushwacker | Chameleon | Chester Goudal | Colonel Ross Whittaker | Cristu Bulat | Daken | Damage | Deadpool | Death Adder | Deke Wainscroft | Dormammu | Eel | Electro | Finn Cooley | Frost | Green Goblin | Grizzly | Hammerhead | Hitman | HYDRA | Jack O' Lantern | Jackal | Jester | Jigsaw | Kesselring | Kingpin | Loki | Ma Gnucci | Madame Viper | Maginty | Mandrill | Mandarin | Mister Hyde | Molten Man | Moses Magnum | Mr. Payback | Nicky Cavella | Norman Osborn | Punisher | Punisher (Earth-95126) | Reavers | Reverend Samuel Smith | Rhino | Roxxon | Russian | Scarecrow | Shocker | Tiberiu Bulat | Tiger Shark | Tombstone | Vulture

Movies
The Punisher (1989): Punisher | Lady Tanaka | Gianni Franco | Tanaka's Daughter
The Punisher (2004): Punisher | Howard Saint | Quentin Glass | Livia Saint | John Saint | The Russian | Harry Heck | Mickey Duka
War Zone: Punisher | Jigsaw | James Russoti | Carmine Gazzera | Ink | Maginty

Television
Season 1: Punisher | Agent Orange | Jigsaw | Lewis Wilson | Blacksmith | Morty Bennett | Carson Wolf | Tony Gnucci | Lance | Paulie | Leo | Turk Barrett
Season 2: Punisher | Anderson Schultz | John Pilgrim | Jigsaw | Eliza Schultz | Krista Dumont | Turk Barrett

           Iron Man Vol 5 logo.png Villains

Comics
A.I.M. | Ani-Men | Arcade | Batroc | Beetle | Black Widow | Blizzard | Blood Brothers | Boomerang | Brothers Grimm | Collector | Commander Kraken | Count Nefaria | Crimson Dynamo | Crossbones | Crusher | Death's Head | Diablo | Doctor Doom | Doctor Octopus | Dreadknight | Ego | Ezekiel Stane | Fin Fang Foom | Firebrand | Fixer | Gargantus | Ghost | Gladiator | Goliath | Godzilla | Grant Ward | Graviton | Griffin | Growing Man | Hammerhead | Hand | HYDRA | Justin Hammer | Kang | Killer Shrike | Living Laser | Lucia Von Bardas | Mad Pharaoh | Madame Masque | Madame Viper | Malekith | Mandarin | Masked Marauder | Melter | Mister Hyde | M.O.D.O.K. | Mole Man | Morgan le Fay | Nitro | Norman Osborn | Obadiah Stane | Omega Red | Paladin | The Punisher (Earth-95126) | Radioactive Man | Red Ghost | Rhino | Ronan | Roxxon | Scarecrow | Secret Empire | Shocker | Shockwave | Simon Krieger | Skrulls | Super-Adaptoid | Super-Apes | Supreme Intelligence | Taskmaster | Technovore | Temugin | Thanos | Ten Rings | Thunderball | Thunderbolt Ross | Thundersword | Tinkerer | Titania | Titanium Man | Ultron | Unicorn | Vermin | Vulture | Warlord Krang | Whiplash | Whirlwind | Wrecker | Yellow Claw | Zodiac

Movies
The Invincible Iron Man: Mandarin | The Elementals | Deities of Death (Dormammu, Hela, Mephisto & Pluto)
Iron Man: Iron Monger | Ten Rings (Raza Hamidmi Al-Wazar, Abu Bakaar, Ahmed & Omar) | William Ginter Riva
Iron Man 2: Whiplash | Hammer Industries (Justin Hammer, Jack & Hammer Drones) | Ten Rings (Ten Rings Agent) | Senator Stern | Anton Vanko
Iron Man 3: A.I.M. (Aldrich Killian, Eric Savin, Trevor Slattery, Ellen Brandt, Sweat Shop Agent, Ponytail Express, Maya Hansen & Extremis Soldiers) | Vice President Rodriguez
Heroes United: Iron Man and Hulk: Zzzax
Heroes United: Iron Man and Captain America: HYDRA (Red Skull & Taskmaster)
All Hail the King: Trevor Slattery | Herman | Ten Rings (Jackson Norriss & The Mandarin) | White Power Dave | Justin Hammer

Television
Iron Man (1994): Mandarin | Whirlwind | Dreadknight | Backlash | Grey Gargoyle | Living Laser | M.O.D.O.K. | Fin Fang Foom | Justin Hammer | Beetle | Crimson Dynamo | Titanium Man | Madame Masque | Dark Aegis
Iron Man: Armored Adventures: Mandarin | Obadiah Stane | Madame Masque | Ghost | Zhang | Dreadknight | Crimson Dynamo | Titanium Man | Black Knight | Whiplash | Doctor Doom | Magneto | Unicorn | Count Nefaria | Fixer | M.O.D.O.K.

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