Crash Bandicoot: The Huge Adventure (XS)
After Crash Bandicoot tricks Dr. Cortex into shrinking the Gems that stabilise his Planetary Minimizer device, the machines unrestrained energy zapped Cortex and his minions which merged them temporarily into the creature known as Mega-Mix. Mega-Mix is infuriated over the incident and tries to destroy Crash out of revenge. However, Crash manages to escape Cortex's space station just before it breaks apart, leaving villains stranded inside the wreckage. Mega-Mix can only be encountered once the player has gathered all the Crystals and Gems in the game.
Crash Bandicoot 2: N-Tranced
Mega-Mix is a playable character in the games multiplayer mode. He is unlocked after the player has acquired Neo Cortex, N. Gin, Tiny Tiger and Dingodile as multiplayer characters.
Crash Team Racing: Nitro-Fueled
Mega-Mix is a playable racer that can be unlocked during the Rustland Grand Prix event by earning Nitro Points. He is a Balanced class driver.
- Mega-Mix is so far the only boss in the Crash Bandicoot series who is completely invincible. The only way for Crash to beat him is by finishing the level he is found in.
- He seems to be a separate character from Cortex, N. Gin, Tiny and Dingodile in Crash Team Racing: Nitro-Fueled, since he is seen playing alongside them, and is even seen hurting Nina, someone whom Cortex cares about.