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I was not born a Pokémon, I was created! And my creators have used and betrayed me! So... I stand alone!
~ Mewtwo to Giovanni.
Humans cannot be trusted. I've told you this. It seems you forgotten that, as well.
~ Mewtwo to Detective Pikachu.
Mewtwo (in Japanese: ミュウツー, Mewtwo), also known as the Genetic Pokémon, is the secondary antagonist of the Pokémon franchise. It is a psychic genetic Pokémon cloned from Mew, the Legendary Pokémon ancestor of all Pokémon. Interestingly, Nintendo (for a time) considered Mewtwo the secondary antagonist of the franchise, behind Giovanni and Meowth. Mewtwo can be considered evil, but more misunderstood because of the way that it was created. Other times, Mewtwo serves as a hero and helps the main cast.
In the anime, he was voiced by Philip Bartlett in the first movie, and later Jay Synder (also known by his alias Dan Green) in Mewtwo Returns and Miriam Pultro in Genesect and the Legend Awakened. In the Super Smash Bros. franchise, he was voiced by Masachika Ichimura in Super Smash Bros. Melee and the late Keiji Fujiwara in Super Smash Bros. for 3DS, Super Smash Bros. for Wii U, and Super Smash Bros. Ultimate. In Detective Pikachu, he was voiced by Chris Smith.
Mewtwo as a clone of Mew so it looks pretty similar to Mew but with some differences. Mewtwo is a tall 6'07 bipedal Pokémon that is mostly gray all around but with a long purple tail, it also has short horns on its head, and a tube that extends from the back of its skull to the top of its spine, bypassing its neck. It also has a defined chest and shoulders, Its tail is thick at the base, but thins before ending in a small bulb.
Mega Mewtwo X is much larger and bulkier than its normal state. The horns on its head are longer and curve upwards more and are more straight than before, its eyes are also now light blue, and it has large, purple growths over its shoulders. Its torso is much smaller than its bulky hands and the rest of its body. Its forearms and thighs each have two raised ridges and its digits are now longer and thinner. The tail is also slightly shorter.
In comparison to Mega Mewtwo X, Mega Mewtwo Y is smaller and lighter, it loses its long tail and the tube behind its neck. However, it grows a long, purple part on its head with a curled tip from the back of its head that is similar to its previous form's tail. Its eyes are now red and slightly larger.
Powers and Abilities
Mewtwo is highly skilled with Psychic powers. It can levitate through use of telekinesis, speak telepathically, and can take control of another living being's mind. It has a powerful signature move, Psystrike (psychic wave manipulation), and it is also known for its powerful Shadow Ball and Aura Sphere. Mewtwo is also capable of wielding various types of attacks (but to a lesser extent than Mew). So as to exert its powerful psychic abilities, it will stay motionless for long periods of time in intense concentration to raise its capabilities to their maximum power.
Its also shown to be able to teleport with ease and fast as well. It is shown to just be fast in general mostly in the air. It can also recover near-fatal damage on a whim.
In its Mega forms, it is even more powerful, shown to be able to go even faster is far stronger and can take more hits.
In the Pokémon Adventures manga, Mewtwo fights with a highly skilled combination of Psywaves and a giant spoon for long-range and close-range battles, respectively.
In the original Japanese release of Mewtwo Strikes Back, Mewtwo is a very different character. He comes off as more sympathetic, with no intention to harm humans. He instead does the things he does in an effort to prove his own worth and believed superiority to the world.
The armor used to restrain Mewtwo in the FireRed and LeafGreen story arc of the Pokémon Adventures manga resembles the armor Mewtwo wore in the anime.
A journal quote from the Pokémon Mansion states that Mewtwo's birthday is February 6.
More directly, however, it bears a strong resemblance to the main antagonist of the Mother series, Giygas, particularly in his appearance in the first Mother (Earthbound Beginnings). A lot of the staff of that game had later worked on Pokémon.
Since Generation V, Mewtwo is the only Pokémon who can learn the move Psystrike.
From Generation V to VII, Mewtwo learns Psystrike at level 100. In Generation VIII, Mewtwo learns Psystrike at level 72 instead.
Mewtwo was also the first Pokémon to use Shadow Ball.
Although the official website for Genesect and the Legend Awakened claimed that the Mewtwo in the film was the same individual as in the first movie and Mewtwo Returns, both a prologue and flashbacks in the movie itself prove it to be completely different from it, including it being female in nature.
Mewtwo is one of the only two villains in the Super Smash Bros. series that was dropped from one installment and then been brought back in the next, the other being Wolf O'Donnell.