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I will follow your instructions, Lord. I have faith in thee.
~ Mom before locking her son, Isaac, in his room.
Isaac!
~ Mom calling out for Isaac.

Magdalene O. Moriah, better known as Isaac's Mother or simply Mom and Mother, is the main antagonist of the roguelike video game The Binding of Isaac and one of the three main antagonists of its remake The Binding of Isaac: Rebirth alongside Satan and Delirium. She is the mother of Isaac and the central force of evil within the game.

She was voiced by Carla Kihlstedt in the original game and by Patty Allen-Scott in The Binding of Isaac: Rebirth.

Biography

Isaac's mother was once a caring individual, but she went insane at some point and began to hear God speaking to her, telling her Isaac was evil and corrupt. Mom proceeded to deny Isaac basic rights and abused him horribly, locking him in his room, removing his clothes and denying her own son almost any form of nourishment or love.

Her madness then reached a climax when she became convinced God had ordered her to kill Isaac so she can show devotion and she prepared to make her son a sacrifice. Despite being a despicable and evil woman, Mom continually praised God and believed she was doing her Lord's work.

Mom also manifests in Isaac's nightmare world as a horrific demon that acts as the final monster he must encounter in the original game, having a massive array of powers and being depicted as a mindless killer. She is also implied to be grotesque in appearance, as many of the items focused around her (Mom's Bra, Mom's Pad, Mom's Contact, etc.) all cause enemies to become petrified.

Isaac's Mother also returns in the expansions, in different incarnations, namely her monstrous Heart, though the expansions do change her role and she is no longer the "final boss" of the actual game. Through implications within the true ending of the Wrath of The Lamb DLC, it is shown that Mom was once married, though her husband, at some point, left, leaving Isaac in her custody.

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Seven Deadly Sins
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The Harbringers
Famine | Pestilence | War | Death | Conquest | Headless Horseman | Ultra Famine | Ultra Pestilence | Ultra War | Ultra Death

Final Bosses
Mom | Mom's Heart | It Lives | Satan | Isaac | The Lamb | ??? | Mega Satan | Ultra Greed | Hush | Delirium | Mother | Dogma | The Beast

Other
Taunted Esau

The Legend of Bum-bo
Bygone | Dusk | Gibs | Gizzarda | Loaf | Peeper | Pyre | Sangre | Shy Gals | The Duke

The Binding of Isaac: Four Souls Warp Zones
Ballos | Balrog | Death Trapper | Expósito | Gorm | Impostors | Leather Neck | Lil' Hunter | Melquíades | Psycho Goreman | Purple-Shirted Eye Stabber | The Butcher | The Collector | The Grandparent | The Radiance | Time Eater | Tony | Y.V.