Dr. Calvin Zabo is a morally abject but brilliant medical researcher who was fascinated by the effect of hormones on human physiology. One of his favourite stories was R.L. Stevenson's 1886 classic, Dr. Jekyll and Mr. Hyde.

History

He was convinced that the experiment in the story could actually be performed and obsessed with the idea of unleashing his full bestial nature in a superhuman form. However, he needed money to do this so he robbed his various employers systematically. Though too intelligent to be caught, the medical community was suspicious of his tendency to always be employed by organizations which were subsequently robbed.

Mr. Hyde in Agents of S.H.I.E.L.D.

He sought work as a surgeon in a hospital where Donald Blake was a directing physician, yet Blake would not allow him a job due to his history. Zabo was enraged that Blake would not give him the position, even though he did indeed intend to rob the organization. He swore revenge on Blake. He was eventually successful in creating the Hyde Formula, and turned into a huge, Hulk-like creature he called "Mister Hyde", named after the Mr. Hyde in the book. In this new form he found he had vast superhuman strength enabling him to crush cars and tear through steel as though it were made of cardboard. With his new superhuman powers he sought out Blake, who transformed into Thor and beat him senseless. He next kidnapped Donald Blake and Jane Foster and even though he was once again defeated by Thor, he managed to escape because Foster had hidden Thor's hammer, fearing that if Hyde was captured, Blake would be killed by a time bomb Hyde had set.

At some point Hyde fathered a daughter, Daisy Johnson, who became a member of S.H.I.E.L.D.; her mother was apparently a prostitute with whom Calvin Zabo regularly had 'business'. The girl was put up for adoption after birth, subsequently manifesting superpowers due to Zabo's mutated genetic code being passed on to her.

He went into business as a full time professional super criminal and partnered himself with the Cobra to get revenge upon Thor. With the Cobra, he was employed by LOki to kidnap Jane Foster, and they battled Thor again, but were defeated even though Loki had doubled their power. Hyde and Cobra were among the many costumed menaces assembled by Doctor Doom to disrupt the wedding of Reed Richards and Susan Storm.

Hyde and the Cobra next battled Daredevil. Cobra then teamed with the original Jester and Cobra against Daredevil. With the Scorpion, Hyde then battled Captain America and the Falcon. Teaming with the Cobra again, Hyde attempted to acquire Cagliostro's serum. Hyde was next employed by the Purple Man, and battled Daredevil in an arena alongside Cobra, the Jester, and the Gladiator.

Hyde and the Cobra frequently fought Thor, Spider-Man, and Daredevil, and were essentially inept criminals. Eventually, tiring of their repeated failures, the Cobra elected to sever their partnership. He escaped from Ryker's Island, taking the time to taunt Hyde before leaving. Hyde never forgave him for the slight. With Batroc, Hyde later blackmailed New York City with a hijacked supertanker. Hyde attempted to destroy the entire city in order to kill Cobra. Eventually, he was defeated by Captain America with Batroc's aid. Hyde then stalked Cobra seeking revenge, and this time battled Spider-Man. He was imprisoned again but escaped Ryker's Island, and stalked Cobra again, and battled Spider-Man and the Black Cat. Hyde later battled Daredevil again.

Masters of Evil

Hyde later became a member of the Masters of Evil IV. With the Masters of Evil, Hyde invaded Avengers Mansion. He tortured the Black Knight and Edwin Jarvis. With Goliath and the Wrecking Crew, he nearly killed Hercules, but was defeated by the Avengers. Hyde later attempted an escape from the Vault alongside Titania, Vibro, the Griffin, and Armadillo. He was defeated and recaptured by the Captain. He later eventually escaped from the Vault alongside the Wizard and others. Hyde was later defeated in combat by the Cobra.

Hyde later fought with the Grey Hulk and received head trauma that limited his ability to transform. Shortly after he had several run-ins with the Dan Ketch Ghost Rider in which he was defeated with the Penance Stare.

Hyde briefly helped the symbiote-bonded Toxin track Cobra after a prison escape by providing a piece of skin for the symbiote to track.

Zabo was being held in The Raft (the Ryker's Island Prison complex.) When a prison break was caused by the villain, Electro, Zabo emerged in his Hyde persona and fought with Daredevil and was knocked unconscious by Luke Cage.

At one point, Zabo was discovered by the Young Avengers to be selling a derivative of his Hyde formula on the street as one of the various illegal substances known as Mutant Growth Hormone.

Civil War

Most recently, Zabo began to graft abilities similar to the powers of Spider-Man to homeless teenagers. After Spider-Man revealed his identity during the Civil War, Zabo sought to recreate the circumstances of Spider-Man's "birth", by taking in orphans off the street, imbuing them with spider-powers, and seeing whether or not the teenagers would give in to their darker impulses. During the ensuing battle with Spider-Man, Hyde pulled webbing off his face, taking his eyelids with it, and was hit in the face with hydrochloric acid, courtesy of one of his own guinea pigs. He was left blinded and his face was ruined as a result. Dr. Curt Connors later aided Spider-Man in a cure for Calvin, one of Zabo's test subjects.

The Hood

The Hood hired him as part of his criminal organization to take advantage of the split in the superhero community caused by the Superhuman Registration Act. Later. along with Firebrand, King Cobra, and Mauler, he attacked Yellowjacket, Constrictor and other Initiative staff and trainees.

Mister Hyde worked with Boomerang, Tiger Shark, and Whirlwind to manipulate Venom into procuring Norman Osborn's fortunes. This was thwarted by Venom and Green Goblin as Norman threw a bomb into Mister Hyde's mouth causing him to spit out blood. Norman Osborn then warned Mister Hyde and the villains that if they crossed him again, he would kill everyone that they ever loved before they were tortured to death.

Thunderbolts

Hyde was recruited into the Thunderbolt's Beta Team.

Powers and Abilities

Mister Hyde posses super strength and invulnerability.

Gallery

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Television
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Avengers: Earth's Mightiest Heroes: HYDRA (Red Skull, Baron Von Strucker, Grim Reaper, Arnim Zola, Doughboy & Madame Viper) | Masters of Evil (Baron Zemo, Enchantress, Skurge, Chemistro, Abomination, Crimson Dynamo & Grey Gargoyle) | A.I.M. (M.O.D.O.K.) | Kree Empire (Supreme Intelligence, Colonel Yon-Rogg & Ronan the Accuser) | Absorbing Man | Klaw | Ultron | Wrecker | Thunderball | Piledriver | Red Hulk | Frost Giants (Loki Laufeyson & Ymir) | Technovore | Bi-Beast | The Leader | Whirlwind | Kang the Conqueror | Man-Ape | Malice | Mad Thinker | Mandrill | Graviton | Fenris Wolf | Lucia Von Bardas | Zzzax | Blizzard | Constrictor | Griffin | Living Laser | Whiplash | King Cobra | Magneto | Wendigo | Skrulls (Super-Skrull) | Malekith the Accursed | Hela | Doctor Doom | Surtur | Glenn Talbot | Winter Soldier | J. Jonah Jameson | Destroyer | Annihilus | Purple Man | Galactus | Firelord | Stardust | Terrax the Tamer
Avengers Assemble: HYDRA/A.I.M. (Red Skull, M.O.D.O.K., Blood Brothers, Grim Reaper, Crossbones & Baron Wolfgang von Strucker) | Doctor Doom | Ulik | Dracula | Hyperion | Wrecker | Thunderball | Piledriver | Destroyer | Loki Laufeyson | Chitauri | Justin Hammer | Mojo | Galactus | Ringmaster | Black Order (Thanos) | Hela | Winter Soldier | Nighthawk | Dormammu | Ultron | Roxxon Energy Corporation | Absorbing Man | Titania | Whirlwind | Fin Fang Foom | Masters of Evil (Baron Zemo, Beetle & Goliath) | Klaw | Ghost | A.I.M. (Kang the Conqueror, Whiplash & Spymaster) | Abomination | Kree Empire | Egghead | The Leader | Crimson Widow | Typhoid Mary | Ares | Taskmaster | Doughboy | Ulik | Symbiotes | Morgan le Fey | Tiger Shark | Erik Killmonger | Man-Ape | Madame Masque | Kraven the Hunter | Vulture

Movies
Ultimate Avengers 1 & 2: Herr Kleiser | Chitauri
Next Avengers: Heroes of Tomorrow: Ultron
The Avengers: Loki Laufeyson | Chitauri (The Other & Leviathans) | HYDRA (Gideon Malick & Jasper Sitwell) | Georgi Luchkov | Thanos
Avengers: Age of Ultron: Ultron | Ultron Sentinels | HYDRA (Wolfgang von Strucker, List, Scarlet Witch & Quicksilver) | Ulysses Klaue | Madame B | Chitauri (Leviathans) | Thanos
Avengers: Infinity War: Black Order (Thanos, Ebony Maw, Proxima Midnight, Corvus Glaive, Cull Obsidian, Nebula, Outriders, Chitauri & Leviathans) | Red Skull | The Collector | Loki Laufeyson | Winter Soldier | M'Baku | Scarlet Witch | Thunderbolt Ross
Avengers: Endgame: Black Order (Thanos, Ebony Maw, Proxima Midnight, Corvus Glaive, Cull Obsidian, Nebula, Outriders, Sakaaran Mercenaries, Chitauri, Leviathans & Chitauri Gorillas) | HYDRA/STRIKE (Red Skull, Alexander Pierce, Crossbones, Jasper Sitwell & Jack Rollins) | Loki Laufeyson | Winter Soldier | M'Baku | Scarlet Witch | Kraglin Obfonteri | Dark Elves | Thunderbolt Ross | Akihiko

Video Games
Marvel's Avengers: M.O.D.O.K. | Monica Rappaccinni | Abomination | Taskmaster | Super-Adaptoid | Lyle Getz

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Movie
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Season 3: Kingpin | Bullseye | Vanessa Marianna

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Movies
Hulk Vs. Thor: Loki Laufeyson | Hela | Enchantress
Thor: Tales of Asgard: Loki Laufeyson
Thor: Loki Laufeyson | Frost Giants (Laufey, Grundroth, Hailstrum, Raze & Jotunheim Beast) | The Destroyer | Jasper Sitwell
Thor: The Dark World: Dark Elves (Malekith the Accursed & Kurse the Strong) | Loki Laufeyson | Marauders (Duhg & Kronan Marauder) | Jotunheim Beast | The Collector
Thor: Ragnarok: Berserker Army (Hela Odinsdottir, Skurge & Fenris Wolf) | Sakaaran Guards (The Grandmaster & Topaz) | Loki Laufeyson | Fire Demons (Surtur & Fire Dragon) | Thanos

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Absorbing Man | Barracuda | Batroc | Belasco | Bullseye | Bushwacker | Chester Goudal | Colonel Ross Whittaker | Cristu Bulat | Daken | Damage | Death Adder | Deke Wainscroft | Dormammu | Eel | Finn Cooley | Frost | Green Goblin | Grizzly | Hammerhead | Hitman | Jack O' Lantern | Jackal | Jester | Jigsaw | Kesselring | Kingpin | Loki | Ma Gnucci | Maginty | Mandrill | Mister Hyde | Molten Man | Moses Magnum | Mr. Payback | Nicky Cavella | Norman Osborn | Punisher | Punisher (Earth-95126) | Reavers | Reverend Samuel Smith | Rhino | Russian | Scarecrow | Shocker | Tiberiu Bulat | Tiger Shark | Tombstone | Vulture

Movies
The Punisher (1989): Punisher | Lady Tanaka | Gianni Franco | Tanaka's Daughter
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War Zone: Punisher | Jigsaw | James Russoti

Television
Season 1: Punisher | Agent Orange | Jigsaw | Lewis Wilson | Blacksmith | Turk Barrett | Tony Gnucci | Lance | Paulie | Leo
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Comics
Absorbing Man | Agony | A.I.M. | Alistair Smythe | Annihilus | Answer | Arcade | Awesome Android | Basilisk | Beetle | Beyonder | Black Cat | Blackie Drago | Blastaar | Blob | Bombshell | Boomerang | Brothers Grimm | Burglar | Bullseye | Bushwacker | Cadaverous | Calypso | Carlton Drake | Carnage | Carrion | Chameleon | Chance | Constrictor | Crime Master | Crossbones | Daemos | Dark Avengers | Deadpool | Demogoblin | Diablo | Doctor Doom | Doctor Faustus | Doctor Octopus | Doppelganger | Dormammu | Electro | Enforcers | Equinox | Fancy Dan | Firelord | Freak | Frightful Four | Ghost | Gog | Goliath | Grant Ward | Graviton | Green Goblin (Norman Osborn, Harry Osborn & Bart Hamilton) | Grey Goblin | Grizzly | Hammerhead | Hand | Hazmat | High Evolutionary | Hitman | Hobgoblin | Human Fly | Hybrid | HYDRA | Hydro-Man | Inheritors | Iguana | Jackal | Jack O' Lantern | Jigsaw | J. Jonah Jameson | Johnny Ohm | Jonas Harrow | Juggernaut | Justin Hammer | Kaine | Karn | Killer Shrike | Kingpin | Knull | Kraven the Hunter | Lasher | Lady Deathstrike | Lightmaster | Living Brain | Lizard | Loki Laufeyson | Madame Viper | Magneto | Mandarin | Man-Spider | Man-Wolf | Mania | Menace | Mephisto | Mesmero | Mister Fear | Mister Hyde | Mister Negative | Mojo | Molten Man | Montana | Morbius | Morlun | Moses Magnum | Mysterio | Nekra | Nightmare | Niles Van Roekel | Nitro | Onslaught | Overdrive | Owl | Ox | Phil Urich | The Prowler | Psycho-Man | Puma | Punisher | Punisher (Earth-95126) | Ramrod | Raze | Red Ghost | Red Skull | Rhino | Rhino II | Richard Fisk | Ringer | Riot | The Rose | Roxxon Energy Corporation | Sandman | Sauron | Scarecrow | Scorcher | Scorpion | Scorn | Scream | Sebastian Shaw | Secret Empire | Sentinels | Seth Youngblood | Shocker | Shriek | Silver Sable | Sinister Six | Skip | Skrulls | Solus | Peter Benjamin Parker | Patton Parnel | Peter Parker | Spider-Man | Spider-Man Revenge Squad | Spider-Slayers | Spot | Street | Super-Apes | Swarm | Symbiotes | Tarantula | Taskmaster | Terminus | Thunderball | Thunderbolts | Tinkerer | Titania | Titanium Man | Tombstone | Trapster | Tyrannus | Ultimatum | Venom (Eddie Brock) | Vermin | Vulture | Walrus | White Rabbit | Will-O'-The-Wisp | Wizard | Worthy | Zodiac

Movies
Spider-Man: Green Goblin | Dennis Carradine | Bank Robbers | Harry Osborn | J. Jonah Jameson
Spider-Man 2: Doctor Octopus | Harry Osborn | J. Jonah Jameson | Green Goblin
Spider-Man 3: Venom | Sandman | New Goblin | J. Jonah Jameson | Green Goblin | Dennis Carradine
The Amazing Spider-Man: Lizard | Gustav Fiers | Cash Register Thief | Norman Osborn
The Amazing Spider-Man 2: Electro | Green Goblin | Donald Menken | Rhino | Alistair Smythe | Ashley Kafka | Felica Hardy | Gustav Fiers | Norman Osborn
Spider-Man: Homecoming: Bestman Salvage (Vulture, Tinkerer, Shocker #1, Shocker #2 & Randy Vale) | Mac Gargan | Aaron Davis
Spider-Man: Into the Spider-Verse: Kingpin | Prowler | Doctor Octopus | Tombstone | Scorpion | Green Goblin | Vanessa Fisk | Richard Fisk
Spider-Man: Far From Home: Mysterio | William Ginter Riva | Victoria Snow | Gutes Guterman | Janice Lincoln | Doug | Elementals (Molten Man, Hydro-Man, Sandman, Cyclone & Elemental Fusion) | Skrulls (Talos) | J. Jonah Jameson

Television
Spider-Man (1967)
Vulture | Green Goblin | Electro | Rhino | Mysterio | Doctor Octopus | Scorpion | Human Fly | Kingpin | Lizard | Spider-Slayer | Sandman | Dr. Matto Magneto | Enforcers (Cowboy & Ox) | Frederick Foswell | J. Jonah Jameson

Spider-Man (1981)
Doctor Doom | Kingpin | Doctor Octopus | Lizard | Black Cat | Sandman | Magneto | Mysterio | Ringmaster | Green Goblin | Sidewinder | Kraven the Hunter | Red Skull | Chameleon | Vulture | Hammerhead | Wizard

Spider-Man and His Amazing Friends
Green Goblin | Kraven the Hunter | Doctor Doom | Swarm | Chameleon | Electro | Brotherhood of Mutants (Magneto, Blob, Toad & Mastermind) | Mysterio | Loki Laufeyson | Ymir | Mordred | Kingpin | Doctor Faustus | Red Skull | Juggernaut | Shocker | Sandman | Dracula | Scorpion | Beetle | Doctor Octopus | A.I.M.

Spider-Man: The Animated Series
Kingpin | Green Goblin (Norman Osborn & Harry Osborn) | Doctor Octopus | Hobgoblin | Venom | Vanessa Fisk | Richard Fisk | Insidious Six (Scorpion, Rhino, Mysterio, Chameleon, Shocker & Vulture) | Black Cat | Lizard | Morbius | Spider-Carnage | Spider-Slayers (Alistair Smythe) | Carnage | Baron Mordo | Dormammu | Silver Sable | Hydro-Man | Prowler | Doctor Doom | Red Skull | Electro | Hammerhead | Tombstone | Kraven the Hunter | Calypso | Herbert Landon | Jackal | Spot | J. Jonah Jameson

Spider-Man: The New Animated Series
Harry Osborn | Electro | Kraven the Hunter | Turbo Jet | Kingpin | Lizard | Shikata | Silver Sable

The Spectacular Spider-Man
Green Goblin | Tombstone | Doctor Octopus | Hammerhead | Venom | Sinister Six (Rhino, Vulture, Electro, Sandman, Mysterio & Kraven the Hunter) | Chameleon | Tinkerer | Enforcers (Shocker, Ricochet & Ox) | Molten Man | Silver Sable | Harry Osborn | Lizard | J. Jonah Jameson | Black Cat | Miles Warren | Frederick Foswell | Calypso | Roderick Kingsley | Morris Bench | Cletus Kasady

Ultimate Spider-Man
Doctor Octopus | Green Goblin | Harry Osborn | Taskmaster | HYDRA (Arnim Zola, Crossbones, Morbius & Baron Mordo) | Sinister Six (Kraven the Hunter, Rhino, Electro, Scorpion, Vulture & Hydro-Man) | Batroc the Leaper | Beetle | Lizard | Frightful Four (Wizard, Trapster & Klaw) | Juggernaut | Sandman | Venom | Loki Laufeyson | The Collector | Grandmaster | Carnage | Wolf Spider | Shocker | Shriek | Swarm | Dracula | Spider-Slayers (Kaine) | Absorbing Man | Abomination | Annihilus | Arcade | Attuma | Awesome Android | Blastaar | Blizzard | Boomerang | Chitauri | Deadpool | Destroyer | Doctor Doom | Dormammu | Skurge | Enforcers (Montana, Fancy Dan, Ox) | Frost Giants | Grizzly | Hammerhead | Jack O'Lantern | Korvac | The Leader | Living Laser | Man-Wolf | Maximus | Melter | Mesmero | M.O.D.O.K. | Molten Man | Mister Negative | Mysterio | Nightmare | Norma Osborn | Phalanx | Sabretooth | Toad | Ulik | Whirlwind | Wrecker | Piledriver | Thunderball | Ymir | Zodiac | Scorpio | Zzzax | J. Jonah Jameson

Spider-Man (2017)
Symbiotes (Venom, Scream, Scorn & Mania) | Dark Goblin | Hobgoblin | Doctor Octopus | Vulture/Goblin King | Alistair Smythe | Rhino | Jackal | Hammerhead | Electro | A.I.M. (M.O.D.O.K.) | Spider-Slayers | Lizard | Tinkerer | Swarm | Scorpion | Sinister Six | Kraven the Hunter | Man-Wolf | Silver Sable | Beetle | Spot | Prowler | Molten Man | Mister Negative | Chameleon | HYDRA (Crossbones & Arnim Zola) | Ghost | Blizzard | Absorbing Man | Crimson Dynamo | Overdrive | Mysterio | Jack O'Lantern | Paladin | Puma | Shocker | Living Brain | Sandman | Technovore | Baron Mordo | Knull | J. Jonah Jameson

Video Games
Spider-Man: Return of the Sinister Six: Sinister Six (Doctor Octopus, Electro, Hobgoblin, Mysterio, Sandman & Vulture)
Spider-Man & Venom: Maximum Carnage: Carnage | Shriek | Doppelganger | Demogoblin | Carrion
Spider-Man & Venom: Separation Anxiety: The Jury | Sentry | Ramshot | Screech | Bomblast | Firearm | Wysper | Life Foundation | Symbiotes (Carnage | Riot | Lasher | Agony | Scream)
Spider-Man (2000): Doctor Octopus | Symbiotes | (Carnage) | Jade Syndicate | Scorpion | Rhino | Mysterio
Spider-Man 2: Enter Electro: Electro | Beetle | Hammerhead | Lizard |Sandman | Shocker
Spider-Man (2002): Green Goblin | Shocker | Vulture | Spider-Slayers | Scorpion | Kraven the Hunter | Dennis Carradine | Harry Osborn | J. Jonah Jameson
Spider-Man 2: Doctor Octopus | Harry Osborn | Rhino | Mysterio | Shocker | Puma | Black Cat | Vulture | Calypso | J. Jonah Jameson
Ultimate Spider-Man: Bolivar Trask | Venom | Vulture | Silver Sable | Shocker | R.H.I.N.O. | Electro | Beetle | Green Goblin | Sandman | Carnage
Spider-Man 3: Venom | Sandman | New Goblin | Lizard | Scorpion | Kraven the Hunter | Calypso | Kingpin | Rhino | Morbius | Shriek | J. Jonah Jameson
Spider-Man: Web of Shadows: Spider-Man | Venom | Kingpin | Black Cat | Vulture | Electro | Tinkerer | Rhino
Spider-Man: Shattered Dimensions: Mysterio | Kraven the Hunter | Hammerhead | Hobgoblin | Electro | Sandman | Vulture | Scorpion | Deadpool | Juggernaut | Silver Sable | Goblin | Serena Patel | Carnage
Spider-Man: Edge of Time: Peter Parker | Atrocity
The Amazing Spider-Man: Spider-Slayers (Alistair Smythe) | Lizard | Rhino | Vermin | Scorpion | Felicia Hardy | Iguana | Nattie
The Amazing Spider-Man 2: Carnage | Kingpin | Green Goblin | Shocker | Kraven the Hunter | Black Cat | Electro | Chameleon | Norman Osborn | Cash Register Thief
Marvel's Spider-Man: Sinister Six (Doctor Octopus, Mister Negative, Electro, Vulture, Rhino & Scorpion) | Inner Demons | Norman Osborn | Silver Sable | Kingpin | Shocker | Tombstone | Taskmaster | Black Cat | Screwball | Hammerhead | Walter Hardy | Yuriko Watanabe
Marvel's Spider-Man: Miles Morales: Roxxon Energy Corporation (Simon Krieger) | The Underground (Tinkerer) | Prowler | Rhino | Kingpin | Norman Osborn | Doctor Octopus | Vulture

          Captain America Logo.png Villains

Comics
Absorbing Man | Adolf Hitler | A.I.M. | Aleksander Lukin | Arcade | Arnim Zola | Awesome Android | Baron Blood | Baron Wolfgang von Strucker | Baron Zemo | Baron Zemo II | Batroc the Leaper | Black Talon | Black Widow | Blitzkrieg | Blizzard | Boomerang | Bullseye | Cache | Constrictor | Count Nefaria | Cowled Commander | Crimson Dynamo | Crossbones | Dark Avengers | Doctor Faustus | Electro | Famine | Firebrand | Fixer | Flag-Smasher | Ghost | Grand Director | Grant Ward | Griffin | Grim Reaper | Heinz Kruger | Herr Kleiser | HYDRA | Hydro-Man | Jack O' Lantern | Killer Shrike | King Cobra | Kingpin | Klaw | Korvac | Lady Deathstrike | Living Laser | Lucia Von Bardas | Machinesmith | Madame Viper | Madcap | Magneto | Man-Ape | Mandarin | Master Man | Mentallo | Mesmero | Mister Hyde | M.O.D.A.M. | M.O.D.O.K. | Mole Man | Moonstone | Nightmare | Nightshade | Obadiah Stane | Punisher | Punisher (Earth-95126) | Quicksand | Red Skull | Rhino | Ringmaster | Ronan | Roxxon | Säurespritze | Scarecrow | Scorpion | Secret Empire | Selene Gallio | Serpent Society | Shocker | Shockwave | Sidewinder | Sin | Skeleton Crew | Slug | Super-Adaptoid | Superia | Super Patriot | Supreme Intelligence | Tarantula | Taskmaster | Terminus | Thanos | Titania | Titanium Man | Trapster | Typhoid Mary | Unicorn | Ultron | Vermin | Whirlwind | Winter Soldier | Worthy | Wrecker | Yellow Claw | Zahnmörder | Zodiac

Movies
Captain America (1990): Red Skull | Valentina de Santis
Captain America: The First Avenger: HYDRA (Red Skull, Arnim Zola, Heinz Kruger, HYDRA Lieutenant & Velt) | Adolf Hitler | Roeder | Hutter | Schneider
Heroes United: Iron Man and Captain America: HYDRA (Red Skull & Taskmaster)
Captain America: The Winter Soldier: HYDRA/STRIKE (Alexander Pierce, Winter Soldier, Crossbones, Jack Rollins, Jasper Sitwell, Russo, Senator Stern, Arnim Zola, Wolfgang von Strucker, List, Scarlet Witch & Quicksilver) | Georges Batroc | Ferdinand Lopez | Gerald Durand
Captain America: Civil War: Helmut Zemo | Thunderbolt Ross | Winter Soldier | Scarlet Witch | HYDRA (Vasily Karpov, Josef & Winter Soldiers) | Hero Mercs (Crossbones)

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