339px-Character MsBitters

Miss Bitters

Ms. Bitters is a minor antagonist in the animated series Invader Zim. She is the teacher of Zim's and Dib's class at Skool.

A tall, slender old woman of unknown origin or age, she is a very grouchy teacher, who has devoid of any positive emotion and full of demonic hatred for children. Ms. Bitters is voiced by the late Lucille Bliss who also voiced Anastasia Tremaine. Her first name is unknown.

In some early episodes, she appears to be covered in cockroaches. When her students displease her, she habitually looms over them, menacingly, with clawed hands and bared teeth, feeding the possibility that she is inhuman. Details on her history is unknown.

Whatever she is, she cannot survive in direct sunlight, as seen in The Voting of the Doomed. In this same episode, she is wearing a black cloak like a vampire, thought to protect her from the sun. She greatly dislikes children, and has expressed frustration at school over-crowding, as well as disdain for traditional holidays such as Halloween and Valentine's Day (although dislike for the latter could be justified, considering an unknown event in the past changed the Valentine's Day tradition from giving out chocolate and cards to giving "Valentine meat slabs"). In the Halloween Spectacular of Spooky Doom, she is revealed to have an even more demonic doppelgänger in an alternate dimension: A gremlin-like creature known as Nightmare Bitters, who is after Dib's head. She tried to get into Dib's true world, but went back after seeing how


Ms. Bitters is very cold, sadistic and behaves more of a corrupt dictator than a classroom teacher. She doesn't really care for her students or their futures whatsoever, she even insults her current students' parents who were her former students for not growing up to be successful or rich. Bitters has no qualms forcing them to use garbage-filled trash cans instead of desks because she refuses to spend any of the school's money on desks, constituting a health hazard for her students. She also forced her students to sell sawdust passed off as candy bars door-to-door and intended to use that money for either her own benefit or the candy company's own benefit and not use that money to buy actual desks for the students. She even imposed ridiculous hall passes on her own students (kicking them out for ludicrous reasons as well) such as a GPS neck bracelet that will explode if outside school perimeters and an iron radiator. She also thoroughly enjoys punishing her students to extreme degrees, such as forcing Dib to clean up Zim's pimple juice that flooded the entire school (which wasn't Dib's fault) with a very tiny sponge instead of a regular-sized kitchen sponge. 


  • She made a voiceless cameo in Enter the Florpus and doesn't appear anywhere in the story outside of Dib's animesque visualization of how the show progressed (possibly because the story seems to take place during summer). It's likely that Ms. Bitters wasn't brought back due Lucille Bliss' death in 2012.


           Invader Zim Villains

Main Characters
Zim | GIR | Gaz Membrane

Irken Empire
Control Brains | Almighty Tallests | Tak | Sizz-Lorr | Mini Moose

Ms. Bitters | Skool Principal

One-Time Antagonists
Nightmare Bitters | Mortos der Soulstealer | Sergeant Hobo 678 | Planet Jackers | Santa Claus | Peepi | Globulous Maximus | Evil Syndicate

           Nickelodeon Villains

TV Series
Ren Höek | Angelica Pickles | Ed Bighead | Lars Rodriguez | Miranda Killgallen | Glowface | Tlaloc | Dr. Blowhole | Gart Default | Coverton | Sta'abi | Leslie Noodman | Amanda Killman

Hey Arnold!
Helga Pataki | Big Bob Pataki | Wolfgang | Edmund | Ludwig | Summer | Arnie Shortman | Big Gino | Burt | Candy (Hey Arnold!) | Cherice | Connie | Nick Vermicelli | LuLu Morrie and Vic | Che | Tommy | Haunted Train | Mickey the Weasel |

'Oh Yeah Cartoons!

Invader Zim
Almighty Tallests | Zim | Gaz Membrane | Tak | Ms. Bitters | Control Brains | Irken Empire | Mortos der Soulstealer | Iggins | Sizz-Lorr | Santa Claus | Mini Moose

Skrawl | Quicksand Man | Vinnie Raton | Terry Bouffant

El Tigre
Sartana of the Dead | Black Cuervo | Voltura | Lady Gobbler | Dr. Chipotle Jr. | Dr. Chipotle Sr. | Señor Siniestro | Django of the Dead | Golden Eagle Twins | Cactus Kid | El Oso | The Bad Girls | Che | General Chapuza | Comrade Chaos | Silver Wolf | El Tarantula | Ninja Monster Clan | Android El Tigre

Back at the Barnyard
Nora Beady | Snotty Boy | Phlegmy Boy | Mertin Fargleman | Cave Cow | Goraldo | Don Bling | Aubrey and Max| Snotty Boy's Friends | Inga | Eddie | Bingo | Swimmy | Polly Ivana Sugardaddy | Prunella | Stinky McStupidhead | Brunhilda | Whiplash McGee | J.T Frittlehoot | Vampire Otis | French-Canadian Crows |

The Mighty B!
Portia Gibbons | Gwen Wu | Cherry | Roxxy | Hal | Mr. Griff | Harris Daye | Robot Bessie | K.G. Bianca | Chelsea Gibbons | Chelsea's Friedns | Finguere |

Fanboy & Chum Chum
Kyle Bloodworth-Thomason | Lenny Flynn - Boyle | Boog Shlizetti | Sigmund the Sorcerer | Mr. Trick | Berry the Ice Monster | Professor Flan | Necronomicon

T.U.F.F. Puppy
Verminious Snaptrap | Francisco | Larry | Ollie | Bad Dog | Chameleon | Katty Katswell | Bird Brain | The Caped Cod | Jack Rabbit | Quacky the Duck | Slush and Snowflake | Madame Catastrophe | Dr. Rabies | Snapbot | King Mutt | Night Mare | Ewe | Overbear |

The Breadwinners
Rambamboo | Oonski the Great | Biker Ducks | Lava Mole | Giant Bacteria Blob | Breadbots | Emerald Loaf | Commander Conch | Camp Counselors | Pond Monster | Captain Goosington | Hotshot | Poltergoose | Mr. Flutterbee | Freaky Finger Bread | Trash Bandit | Pizza Lord | Zoona and Roni | Bread Foot | Crazy Dentist | P.B. | Ponda Gang | Dishwasher | Ducktor Quazy | Hunch Butt | Robo Toilet 3000 | Rusty | Giant Birthday Cake | Three Headed Birdman | French Chef | Giant Fire Breathing Baby Chick | Giant Underpants | Alley Monsters |

The Loud House
Exterminator | Flip | Tetherby | Hawk & Hank | The Hazeltucky Hocker | Park Ranger | Chandler | Bratty Kid | The Manager | Sue | Principal Huggins | Street Cats | Petey | Michelle and Doug | The Kitty Lacey St. Clair

It's Pony
Henrietta Sneekly | Jill Sneekly |

Ned's Declassified School Survival Guide

The Thundermans
Max Thunderman | Dark Mayhem

Nevel Papperman | Lewbert Slime | Nora Dershlit | Chuck Chambers | Mr. and Mrs. Dershlit

Jade West

Game Shakers

Knight Squad

I Am Frankie

Henry Danger
Henry Danger Villains

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