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Poison is one of the criminals who are members of the Mad Gear Gang and an antagonist in the Final Fight video game series.
Poison was one of the few females of the Mad Gear Gang, who rank among the most insidious members of the Gang. After the fall of the Mad Gear Gang, Poison became Hugo's manager in the wrestling world, serving as the driving force behind one of the most dangerous athletes in the world.
She later made cameo appearances in Street Fighter Alpha 2, Street Fighter III: 3rd Strike and SvC Chaos: SNK VS Capcom. She made playable appearances only in Final Fight Revenge, Street Fighter X Tekken, Ultra Street Fighter IV, and Street Fighter V.
- It is said that in the American release of Final Fight, Capcom stated Poison to be a transgender when questioned about the fact players were allowed to hit the female characters Poison and Roxy, as it was highly frowned upon that time in America. However, in some old profiles and concepts for Poison, she was described in Japanese as a newhalf: the Japanese name for a transgender woman. Anyway, in the American release of the game for SNES, Poison and Roxy were replaced by two frail-looking men, named Billy and Sid.
- In the original Final Fight, her palette swap is known as Roxy, who differs from Poison in that she has orange hair, while Poison has pink.
- Poison was going to be one of the bosses in the game Final Fight: Streetwise, but she was removed from the game alongside Sodom, and replaced by Cammy.
- Poison was going to appear also in the cancelled game Capcom Fighting All-Stars, alongside many other Capcom characters. Capcom Fighting All-Stars came out instead, but Poison was nowhere to be seen.
- Poison has appeared in the Street Fighter III series and in SvC Chaos: SNK VS Capcom in Hugo's intros and winposes, in SvC she also had dialogues with the other characters.
- Poison and the Mad Gear Gang have cameos in the background of Metro City stage in Marvel VS Capcom 3: Fate of Two Worlds/Ultimate Marvel VS Capcom 3. She is seated on a fallen statue of Haggar, watching the battle.
- Capcom tried to believe the fact that Poison is a transgender female in the games after Final Fight. However, in Capcom Classics Collection, her profile says that she is a man who dress female clothes and in Street Fighter X Tekken, some commentaries of the other characters about her suggest that she is a transgender although this was later omitted.