Regan Matthews was a LuthorCorp executive and a recurring antagonist in the WB/CW TV series Smallville. He appeared as the main antagonist in the Season Eight premiere "Odyssey".
He was portrayed by Ari Cohen.
When Lex Luthor was getting ready to leave to Zurich to open the box after he had obtained the two Veritas keys, Regan came into his office and informed him that he's been red-flagged by the government and his departure has been delayed.
After Lex was attacked by a mysterious stranger in the mansion, he was taken to the hospital where Regan paid him a visit. Lex ordered him to keep a close eye on the antique dealer Milash who was studying the cryptograph that Lex found in Zurich.
Lex was in his Daily Planet office when Regan informed him that two of his teams have gone missing trying to reach their target in the Arctic Circle. Jimmy Olsen then appeared and wanted to end his deal with Lex as he didn't want to lie anymore to Lois or Chloe. Lex had Regan escort him out. Regan then accompanied Lex to the arctic on the LuthorCorp jet.
Regan was temporarily in charge of LuthorCorp after Lex went missing and was heading the Arctic search team. Tess Mercer arrived in a helicopter and assumed control by Lex's written instructions. One of the scientists found some human remains in the snow when they were ambushed and attacked by the Justice League. He tried to attack Green Arrow but was subdued by Aquaman.
He then went to the Black Creek facility where Ray had forced Chloe Sullivan. who had super intelligence after Brainiac attacked her, to decipher the last phone number of Green Arrow using a mind control serum taken from Moira Sullivan's spinal fluid. Once he located Green Arrow, Regan controlled him with the same serum and commands him to find out what happened to Lex Luthor at all costs. Under the influence of the drug, Oliver shot a powerless Clark Kent with an arrow.
Tess later had the facility shut down, releasing all the inmates and Regan went underground. Months later, Regan returned to Metropolis because Tess was asking questions about Project Prometheus. Regan insisted he was trying to save Lex unlike Tess. He also refused to divulge any information and also after he rejected her job offer in favor of staying loyal to Lex.
When she returned to the Planet, Reagan was there to prevent her from getting more information about Prometheus by killing her messenger, after he gave up the location of Lex's lab. Tess says she has security cameras that will have recorded her guard's death, and Regan boasts that he viewed some of the recordings Lex made of her. Regan prepares to shoot her but Tess disarms him with a trophy, fells him and she began kicking him repeatedly until his blood splatters on her face.
However, Tess did not kill Regan. Much later, Lois saw a video of Tess interrogating Regan about the Orb.