Regan Matthews was a LuthorCorp executive and a recurring antagonist in the WB/CW TV series Smallville. He appeared as the main antagonist in the Season Eight premiere "Odyssey".
He was portrayed by Ari Cohen.
When Lex Luthor was getting ready to leave to Zurich to open the box after he had obtained the two Veritas keys, Regan came into his office and informed him that he's been red-flagged by the government and his departure has been delayed.
After Lex was attacked by a mysterious stranger in the mansion, he was taken to the hospital where Regan paid him a visit. Lex ordered him to keep a close eye on the antique dealer Milash who was studying the cryptograph that Lex found in Zurich.
Lex was in his Daily Planet office when Regan informed him that two of his teams have gone missing trying to reach their target in the Arctic Circle. Jimmy Olsen then appeared and wanted to end his deal with Lex as he didn't want to lie anymore to Lois or Chloe. Lex had Regan escort him out. Regan then accompanied Lex to the arctic on the LuthorCorp jet.
Regan was temporarily in charge of LuthorCorp after Lex went missing and was heading the Arctic search team. Tess Mercer arrived in a helicopter and assumed control by Lex's written instructions. One of the scientists found some human remains in the snow when they were ambushed and attacked by the Justice League. He then went to the Black Creek facility and forced Chloe Sullivan who had super intelligence after Brainiac attacked her, to decipher the last phone number of Green Arrow using a mind control serum taken from Moira Sullivan's spinal fluid. Once he located Green Arrow, Regan controlled him with the same serum and commands him to find out what happened to Lex Luthor at all costs. Under the influence of the drug, Oliver shot a powerless Clark Kent with an arrow.