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Reign Sison is the main antagonist of the 2019 Filipino drama series, Bihag (Captive). She is the cruelest and malevolent mistress who torments her cousin, she is also Jessie's formidable enemy, her schemes are far above than normal villains as she crosses Moral Event Horizon. She is seen as an immensely ruthless, calculating and greedy, as she only cares about herself and even killed Brylle's mother to frame up Jessie. She killed few characters in the series including Ethan. Her atrocious acts are purely evil. She is also a wealthy woman who paid many goons to kill her nemesis.

She was portrayed by Filipino actress Sophie Albert.

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