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No wife. No life. No home. Vengeance... it's all you have.
~ Santino D'Antonio
Winston: Jonathan, just walk away.
Santino: Yeah, Jonathan. Walk awa-
~ Santino's last words before Jonathan "John" Wick shoots him dead

Santino D'Antonio is the main antagonist of the 2017 film John Wick: Chapter 2 and a posthumous antagonist in John Wick: Parabellum.

He is an Italian Mafia boss and the head of the D'Antonio Crime Family. He seeks to join the High Table by killing his sister and taking her seat.

He was portrayed by Riccardo Scamarcio.


Pre-John Wick

John Wick, to complete his "impossible task" assigned by Viggo Tarasov, which allowed him to retire and marry his deceased wife, Helen, asked Santino for help. As a form of contract, Santino swore John to a "Marker," an unbreakable promise symbolized by a "blood oath" medallion.

John Wick: Chapter 2

A few days after John came out of retirement to seek revenge on Viggo and Iosef, Santino decides to visit John Wick and presents the medallion to demand service from him. However, John refuses to honor the oath, claiming that he is retired. Santino leaves the house displeased, and opens the back of his truck, revealing a grenade launcher which he uses to destroy the house.

John later decides to honor his oath, with some convincing from Winston, and goes to see Santino to find out what his mission for him is. Santino tasks him with assassinating his sister, Gianna D'Antonio, so he could take her spot at the High Table, a council of leaders of the world's most powerful criminal organizations.

After John succeeds in his mission, Santino sends Ares, his personal (and mute) bodyguard, and several of his goons to kill John to tie up loose ends. However, John kills most of his men and escapes. Santino then tries to phone call John, but Wick refuses to listen. Santino then places a $7 million bounty on John Wick's head, prompting hitmen from all over the world to try and assassinate him.

Santino opening a contract to kill John Wick.

John fends off most of the assassins, but is wounded while doing so. He later finds out Santino's location at an art exhibit from the Bowery King. John goes to confront the Mafia boss while he is holding a party. Upon noticing John, Santino quickly flees while his henchmen fight the ex-hitman.

Santino escapes into the "Reflections of the Soul" exhibit and mocks John, saying he has nothing left but revenge. While John heads into the exhibit to confront him, Ares arrives with several grunts. Although John manages to kill all of the grunts as well as Ares, Santino manages to escape.

Santino just before Wick shoots and kills him.

Santino flees to the Continental Hotel, knowing that John can't kill him there because the rules forbid it. While there, Santino demanded that Winston revoke John's membership to the Continental, but Winston refused as John had not broken any rules. When John arrives in search of Santino and confronts him as he is eating, Santino smugly makes it clear to John that he intends to remain in its sanctuary indefinitely, protected by the rules. However, despite Winston's warnings, John knows full well that even if he lets Santino live, he will still be hunted and then shoots and kills Santino in the Continental lounge much to the shock and dismay of Winston and everyone present.

The next day. John meets Winston at the Bethesda Fountain. Winston informs him that as a direct result of Santino's death, Santino's contract is, per the High Table, doubled and offered globally. John is also declared "excommunicado" from the Continental as a consequence for killing Santino on organization grounds, losing access to the Continental's resources and privileges, almost certainly dooming him to a future of being actively hunted by assassins. However, Winston give John and his dog a 1-hour headstart to run, even giving John a Marker for future use.

John Wick Chapter 3: Parabellum

After his death, it was planned that his body was to be cremated by the furnace on the underground of the Continental Hotel that was used by Charlie and his cleaning crew to dispose bodies. Before that happens, The Adjudicator visits the Continental Hotel and examines his body, while discussing Winston's involvement with John, and how that will serve as a detriment.



  • Even if John Wick never violated the rule of the Continental in not killing Santino, the result would be the same as Santino will just pour his money to make huge bounty on John's head forever. As the result, John decided to kill him was right choice since at least he could get his revenge.
  • It is indicated that both Winston and Charon despise him due to his action in hiring people to kill his sister as Winston coldly refuses his pledge to revoke Wick's membership and Charon simply ignores Wick when he knew fully well that Wick came to kill Santino.
  • Judging his impulsive nature of forcing John Wick to kill sister and hire assassins to kill him, it is possible that his father chose his sister over him as he was unfit to lead the crime family. 


           JohnWickTitle.png Villains

Tarasov Crime Family
Viggo Tarasov | Iosef Tarasov | Avi | Ms. Perkins | Kirill | Abram Tarasov

D'Antonio Crime Family
Santino D'Antonio | Ares | Gianna D'Antonio | Cassian

High Table
The Adjudicator | Zero | Winston | The Elder | The Shinobi

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