Shriek is a criminally insane supervillainess and an enemy of Spider-Man.
Frances Louise Barrison spent her childhood being abused by her mother for being overweight. She was driven to drug use and developed a fixation of becoming a mother herself. Barrison eventually became a drug dealer, leading her into several situations that were harmful to her sanity, including being shot in the head by a police officer. She eventually ended up in Cloak's dark dimension, which caused her to develop the ability to manipulate sound.
Shriek was incarcerated in the criminal mental hospital, Ravencroft, when Carnage caused a mass breakout. Upon seeing their mutual psychopathic sadism, the two "fell in love" and formed a partnership, going on a killing spree. They also teamed up with three other homicidal villains, Demogoblin, Carrion, and Doppleganger, forming a "family". However, they were stopped by Spider-Man, Venom, and Black Cat. Shriek has since tried escaping Ravencroft several times, each time battling Spider-Man.
Shriek can manipulate sound in different ways. She has the hyper sonically tap into people's minds and bring out their inner darkness (generating fear, anger, hate), making them act in violent manners. She can harness it and shoot destructive sonic energy blasts from her hands or disorientate. She can also shield herself with a sonic field and fly. With her sonic powers she is also capable of generating a sonic scream with can deafen or disorientate.