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He worked with Crewman Harlan Burke. After Chancellor Gorkon was brought on board the Enterprise Samno and Burke traded racist remarks regarding the Klingons before they realized fellow conspiracy member Valeris was still in the room. (Not only that, but both Spock and the Klingons heard them due to their sensitive hearing). Valeris asked the two men if they had work to do, and ordered them to set about preparing to assassinate Gorkon.
Later that night, after Gorkon had returned to his ship, Klingon General Chang had his cloaked bird of prey fire on Gorkon's ship Qo'noS 1 in a way that made it appear that Enterprise had fired upon Qo'noS 1. During the confusion Samno and Burke beamed aboard Qo'noS 1, which had experienced gravity failure. The two men wore suits and magnetic boots. The pair located Gorkon and fatally wounded him with a phaser.
A few days later, Valeris realized that Spock and the senior staff of the Enterprise would soon determine that Samno and Burke had been the assassins. Knowing that Samno would expose her and the other conspirators, she lured him and Burke to a corridor, where she killed them with a phaser on stun at close range. Samno's death lead to Valeris being exposed as the traitor.