Vanessa Webber worked for the US Department of Domestic Security as a Special Agent in the CW Television series Smallville.
She appeared as the main antagonist in the Season Seven episode "Sleeper".
She was portrayed by Anne Openshaw.
After Chloe Sullivan had broken into several government databases to try and locate Brainiac and Kara, Vanessa Webber came to Smallville to investigate. She first spied on her and Jimmy Olsen at their apartment at the Talon, surveying him through the window.
Vanessa then approached Jimmy at the Talon coffee shop first acting coy with him then accused him him of hacking into the NSA mainframe. She then introduced herself as an agent of the Department of Domestic Security and tells him that she has been watching him and tracked an infiltration to his computer.
Jimmy claimed he is innocent and Vanessa admits that they were actually targeting his girlfriend, who they thought was working for a terrorist sleeper cell. Jimmy didn't think Chloe was dangerous but Vanessa countered that Chloe has probably been hiding her tracks well by "working late" or missing dates.
She threatened Jimmy with jail time unless he worked with them to spy on Chloe.
She then gave him a briefcase full of spy gadgets. After planting the spyware on Chloe's computer at the Isis Foundation, Jimmy discovered several government firewalls that have been accessed.
Chloe was unsuccessful in hacking into a satellite control center located in the City Center. She looked for a way into the building when she notices the Center contains a club opening that evening: the Ace of Clubs.
Jimmy tried to call Chloe, saying he made a mistake but Vanessa caught him. He tells her that he found nothing suspicious but Vanessa knew he was lying. She tells him that Chloe's plan was going down tonight and his job was to accompany Chloe to the Ace of Clubs party. She gave him a bow tie with a camera inside.
During the party at the Ace of Clubs, Jimmy and Chloe danced before separating to do their jobs. Jimmy believes he retrieved the information Agent Webber wanted and returns to the party to give Vanessa the PDA, claiming he got to the information before Chloe.
Vanessa looks at the data and figures out that Chloe purposefully lured Jimmy to useless files. She decides to take matters into her own hands and threatens to put them both in prison.
Chloe finds a space image which she emails to herself just as Vanessa enters and arrests her. Jimmy is being escorted out of the building, but he escapes the guard and goes to rescue Chloe. Vanessa punches Chloe across the face as she interrogates her but Chloe doesn't co-operate.
Jimmy distracts Vanessa and the guards by uploading his video game onto the satellite screens. Just as Vanessa was about to electrocute her, Jimmy knocked her and another DDS agent unconscious and rescued Chloe.
In response to a request by Jimmy, Lex Luthor persuaded the DDS to drop the charge against Chloe.