In film, she was portrayed by Rachelle Lefevre in Twilight and Twilight: New Moon, and later played by Bryce Dallas Howard in Twilight: Eclipse who also played Hilly Holbrook. Along with Aro, she is considered the main antagonist of the series.
After James was killed by Edward Cullen and his family, Victoria swore revenge against the Cullens by attempting to kill Edward's mate Bella Swan.
In New Moon, she sends Laurent to track down Bella and the Cullens, so that she can kill them. However, he decides to do the job himself, only to be killed by the wolves. Later, she is tracked down by werewolves and Charlie and ends up causing Harry to have a heart attack.
In Eclipse, she forms a pack of newborn vampires to go after Bella, knowing that they will be virtually unstoppable. She manipulates Riley Biers into helping her and being the front man of the operation, while she orchestrates from behind the scenes. During the battle, she and Riley attack Bella and Edward on the mountain, only for Riley to be killed by Seth. Victoria attempts to flee until Edward tricks her into staying and fighting by badmouthing James. The two of them fight until Edward manages to decapitate her and burn her body.
- Despite having a relatively small physical role, she is considered the main antagonist in New Moon, as she is the one directly out to get the Cullens and Bella and causing the trouble, while the Volturi are technically only doing their job.