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The Villain Factory is the enigmatic main antagonistic faction of the 2016 Japanese superhero My Hero Academia spin-off manga series My Hero Academia: Vigilantes.

Little to nothing is known about the secretive criminal organization referred to as the Villain Factory by authorities. The Factory was responsible for the concoction and distribution of powerful quirk-enhancing drugs that dulled the rationality of its consumers and essentially turned ordinary people into rampaging villains. They also biologically engineered people so that they could consume large amounts of their drug, allowing for fare more power.

Operatives such as Number 6 and Kuin Hachisuka answered to a man who contacted them via phone and never showed his face. They were tasked with the distribution of the drug so that data could be gathered regarding the affects of the substance. Their main goal was allegedly to create an entity capable of defeating Japan's greatest and most powerful hero—All Might.

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League of Villains
All For One | Tomura Shigaraki | Kurogiri | Daruma Ujiko | Gigantomachia
Vanguard Action Squad: Dabi | Himiko Toga | Spinner | Twice | Mr. Compress | Muscular | Moonfish | Mustard | Magne | Chainsaw Nomu
Nomus: Kurogiri | Nomu | Chainsaw Nomu | Hood | Johnny | Mocha | Woman
Associates: Giran

Shie Hassaikai
Leaders: Overhaul | Chronostasis | Mimic
Eight Bullets: Rikiya Katsukame | Shin Nemoto | Kendo Rappa | Toya Setsuno | Yu Hojo | Soramitsu Tabe | Deidoro Sakaki | Hekiji Tengai

Meta Liberation Army
Grand Commander: Re-Destro
Leaders: Curious | Trumpet | Skeptic
Warriors: Geten | Slidin' Go
Original Members: Destro

Paranormal Liberation Front
Grand Commander: Tomura Shigaraki
Lieutenants: Dabi | Himiko Toga | Twice | Mr. Compress | Spinner | Re-Destro | Trumpet | Skeptic | Geten
Warriors: Gigantomachia | Slidin' Go
Associates: Daruma Ujiko | Giran

Villain Factory
Kuin Hachisuka | Number 6

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Others
Endeavor | Ending | Gentle | Innsmouth | Kotaro Shimura | La Brava | Peerless Thief | Reservoir Dogs | Stain | Starservant | Sludge Villain

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